Measuring Gastric pH in Tube-fed Children With Neurologic Impairments and Gastroesophageal Disease.
J Pediatr Gastroenterol Nutr
; 72(6): 842-847, 2021 06 01.
Article
em En
| MEDLINE
| ID: mdl-33605659
ABSTRACT
OBJECTIVES:
The aim of the study was to determine the extent of agreement between pH paper and handheld pH meter with a laboratory pH meter for gastric pH measurement in children with neurologic impairments and gastrostomy tubes who have gastroesophageal reflux disease (GERD).METHODS:
In this prospective observational study, gastric contents were aspirated from gastric or nasogastric tubes and the pH measured using 3 techniques pH paper, handheld pH meter, and laboratory pH meter (the gold standard). Agreement between techniques was assessed with intraclass correlation coefficient (ICC), Bland-Altman analysis, and kappa statistic.RESULTS:
Among 43 patients contributing 67 gastric samples, the ICC was 0.75 (95% confidence interval [CI] 0.69-0.97) between the handheld and laboratory meters, 0.69 (95% CI 0.63--0.94) between the pH paper and laboratory meter and 0.69 (95% CI 0.63-0.94) between the handheld meter and paper. The Bland-Altman analysis between the handheld and lab meters showed a mean difference of -0.03 pH units (limits of agreement -0.52 to 0.47 pH units) and 0.17 pH units (limits of agreement -0.99 to 1.33 pH units) between the paper and lab meter. The kappa coefficients for a pH ≥4 were 1.0 (95% CI 1.0--1.0) between the handheld and lab meters and 0.9 (95% CI 0.77--1.0) between the paper and lab meter.CONCLUSIONS:
The findings suggest that both point-of-care tests, the pH meter and pH paper, correlate well with the gold standard for testing pH with a laboratory pH meter, indicating usefulness in point-of-care testing for monitoring gastric pH in tube-fed children with neurologic impairments and GERD.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Nutrição Enteral
/
Intubação Gastrointestinal
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
Limite:
Child
/
Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article