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Endovascular treatment of complicated versus uncomplicated acute type B aortic dissection.
Spinelli, Domenico; Weaver, Fred A; Azizzadeh, Ali; Magee, Gregory A; Piffaretti, Gabriele; Benedetto, Filippo; Miller, Charles C; Sandhu, Harleen K; Gable, Dennis R; Trimarchi, Santi.
Afiliação
  • Spinelli D; Unit of Vascular Surgery, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, Policlinico G. Martino, University of Messina, Messina, Italy. Electronic address: dr.spinelli@me.com.
  • Weaver FA; Division of Vascular Surgery and Endovascular Therapy, University of South California, Los Angeles, Calif.
  • Azizzadeh A; Division of Vascular Surgery, Heart Institute for Vascular Therapeutics, Cedars Sinai, Los Angeles, Calif.
  • Magee GA; Division of Vascular Surgery and Endovascular Therapy, University of South California, Los Angeles, Calif.
  • Piffaretti G; Vascular Surgery, Department of Medicine and Surgery, University of Insubria School of Medicine, Varese, Italy.
  • Benedetto F; Unit of Vascular Surgery, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, Policlinico G. Martino, University of Messina, Messina, Italy.
  • Miller CC; Department of Cardiothoracic and Vascular Surgery, McGovern Medical School, University of Texas Health Science Center, Houston, Tex.
  • Sandhu HK; Department of Cardiothoracic and Vascular Surgery, McGovern Medical School, University of Texas Health Science Center, Houston, Tex.
  • Gable DR; Department of General and Vascular Surgery, Baylor Plano Heart Hospital, Plano, Tex.
  • Trimarchi S; Department of Clinical and Community Sciences, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.
J Thorac Cardiovasc Surg ; 165(1): 4-13.e1, 2023 01.
Article em En | MEDLINE | ID: mdl-33612294
OBJECTIVE: The study objective was to analyze the outcomes of thoracic endovascular aortic repair performed for complicated and uncomplicated acute type B aortic dissections. METHODS: Patients from WL Gore's Global Registry for Endovascular Aortic Treatment who underwent thoracic endovascular aortic repair for acute type B aortic dissections were included, and data were retrospectively analyzed. RESULTS: Of 5014 patients enrolled in the Global Registry for Endovascular Aortic Treatment, 172 underwent thoracic endovascular aortic repair for acute type B aortic dissections. Of these repairs, 102 were for complicated acute type B aortic dissections and 70 were for uncomplicated acute type B aortic dissections. There were 46 (45.1%) procedures related to aortic branch vessels versus 15 (21.4%) in complicated type B aortic dissections and uncomplicated type B aortic dissections (P = .002). The mean length of stay was 14.3 ± 10.6 days (median, 11; range, 2-75) versus 9.8 ± 7.9 days (median, 8; range, 0-42) in those with complicated type B aortic dissections versus those with uncomplicated acute type B aortic dissections (P < .001). Thirty-day mortality was not different between groups (complicated type B aortic dissections 2.9% vs uncomplicated acute type B aortic dissections 1.4%, P = .647), as well as aortic complications (8.8% vs 5.7%, P = .449). Aortic event-free survival was 62.9% ± 37.1% versus 70.6% ± 29.3% at 3 years (P = .696). CONCLUSIONS: In the Global Registry for Endovascular Aortic Treatment, thoracic endovascular aortic repair results for complicated type B aortic dissections versus uncomplicated acute type B aortic dissections showed that 30-day mortality and perioperative complications were equally low for both. The midterm outcome was positive. These data confirm that thoracic endovascular aortic repair as the first-line strategy for treating complicated type B dissections is associated with a low risk of complications. Further studies with longer follow-up are necessary to define the role of thoracic endovascular aortic repair in uncomplicated acute type B dissections compared with medical therapy. However, in the absence of level A evidence from randomized trials, results of the uncomplicated acute type B aortic dissection patient cohort treated with thoracic endovascular aortic repair from registries are important to understand the related risk and benefit.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Aneurisma da Aorta Torácica / Implante de Prótese Vascular / Procedimentos Endovasculares / Dissecção Aórtica Tipo de estudo: Clinical_trials Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Aneurisma da Aorta Torácica / Implante de Prótese Vascular / Procedimentos Endovasculares / Dissecção Aórtica Tipo de estudo: Clinical_trials Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article