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CRISPR/Cas9-edited PKP2 knock-out (JMUi001-A-2) and DSG2 knock-out (JMUi001-A-3) iPSC lines as an isogenic human model system for arrhythmogenic cardiomyopathy (ACM).
Janz, Anna; Zink, Miriam; Cirnu, Alexandra; Hartleb, Annika; Albrecht, Christina; Rost, Simone; Klopocki, Eva; Günther, Katharina; Edenhofer, Frank; Ergün, Süleyman; Gerull, Brenda.
Afiliação
  • Janz A; Comprehensive Heart Failure Center (CHFC), Department of Cardiovascular Genetics, University Clinics Würzburg, Würzburg, Germany.
  • Zink M; Comprehensive Heart Failure Center (CHFC), Department of Cardiovascular Genetics, University Clinics Würzburg, Würzburg, Germany.
  • Cirnu A; Comprehensive Heart Failure Center (CHFC), Department of Cardiovascular Genetics, University Clinics Würzburg, Würzburg, Germany.
  • Hartleb A; Comprehensive Heart Failure Center (CHFC), Department of Cardiovascular Genetics, University Clinics Würzburg, Würzburg, Germany.
  • Albrecht C; Comprehensive Heart Failure Center (CHFC), Department of Cardiovascular Genetics, University Clinics Würzburg, Würzburg, Germany.
  • Rost S; Institute of Human Genetics, Biocentre, University of Würzburg, Würzburg, Germany.
  • Klopocki E; Institute of Human Genetics, Biocentre, University of Würzburg, Würzburg, Germany.
  • Günther K; Institute of Molecular Biology & CMBI, University of Innsbruck, Innsbruck, Austria; Institute of Molecular Regenerative Medicine, Spinal Cord Injury and Tissue Regeneration Center Salzburg, Paracelsus Medical University, Salzburg, Austria.
  • Edenhofer F; Institute of Molecular Biology & CMBI, University of Innsbruck, Innsbruck, Austria.
  • Ergün S; Institute of Anatomy and Cell Biology II, University of Würzburg, Würzburg, Germany.
  • Gerull B; Comprehensive Heart Failure Center (CHFC), Department of Cardiovascular Genetics, University Clinics Würzburg, Würzburg, Germany; Department of Medicine I, University Clinics Würzburg, Würzburg, Germany. Electronic address: gerull_b@ukw.de.
Stem Cell Res ; 53: 102256, 2021 05.
Article em En | MEDLINE | ID: mdl-33640690
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Pluripotentes Induzidas / Cardiomiopatias Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Pluripotentes Induzidas / Cardiomiopatias Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article