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[Network Meta-analysis of Chinese patent medicine in treatment of unstable angina pectoris].
Zhang, Lu-Miao; DU, Ting-Hai; Niu, Lin-Lin; Wang, Lu-Yao; Li, Jun-Nan; Ma, Ping-Fan; Yu, Rui.
Afiliação
  • Zhang LM; Henan University of Chinese Medicine Zhengzhou 450000, China.
  • DU TH; the First Affiliated Hospital of Henan University of Chinese Medicine Zhengzhou 450000, China.
  • Niu LL; the First Affiliated Hospital of Henan University of Chinese Medicine Zhengzhou 450000, China.
  • Wang LY; Henan University of Chinese Medicine Zhengzhou 450000, China.
  • Li JN; Henan University of Chinese Medicine Zhengzhou 450000, China.
  • Ma PF; Zhengzhou Shuqing Medical College Zhengzhou 450000, China.
  • Yu R; the First Affiliated Hospital of Henan University of Chinese Medicine Zhengzhou 450000, China.
Zhongguo Zhong Yao Za Zhi ; 46(3): 703-711, 2021 Feb.
Article em Zh | MEDLINE | ID: mdl-33645038
ABSTRACT
Network Meta-analysis was used to compare the efficacy and safety of Chinese patent medicines in the treatment of unstable angina pectoris. PubMed, Cochrane Library, CNKI, Wanfang, VIP and other databases were retrieved by computers from the establishment of the databases to June 2020. Randomized controlled trials(RCTs) of Chinese patent medicines for the treatment of unstable angina pectoris were collected. Two investigators independently screened out the literatures, and extracted data according to the inclusion and exclusion criteria. The quality of the included RCTs was evaluated according to the bias risk assessment tool recommended by the Cochrane System Reviewer Manual, and the Stata 13.0 software was used for data analysis and mapping. Through screening, 28 eligible studies were finally included, with the sample size of 2 885 cases, involving 8 Chinese patent medicines. The results of the network Meta-analysis showed that in terms of total effective rate for angina symptom improvement, the order was as follows Shenshao Capsules > Naoxintong Capsules > Ginkgo Ketone Ester Dripping Pills > Compound Danshen Dripping Pills > Ginkgo Leaf Tablets > Shexiang Baoxin Pills > Tongxinluo Capsules > Yindan Xinnaotong Soft Capsules; in terms of total effective rate for ECG curative effect, the order was as follows Ginkgo Ketone Ester Dripping Pills>Compound Danshen Dripping Pills > Tongxinluo Capsules > Shenshao Capsules > Shexiang Baoxin Pills > Yindan Xinnaotong Soft Capsules; in terms of hypersensitivity-C-reactive protein curative effect, the order was as follows Tongxinluo Capsules > Shenshao Capsules > Ginkgo Leaf Tablets>Compound Danshen Dropping Pills> Shexiang Baoxin Pills > Naoxintong Capsules > Yindan Xinnaotong Soft Capsules > Ginkgo Ketone Ester Dropping Pills. Chinese patent medicine combined with conventional therapy can improve the clinical efficacy of unstable angina pectoris. Due to the differences in the quantity and quality of the included studies, the order results of Chinese patent medicines need to be further verified.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Medicamentos de Ervas Chinesas / Medicina Tradicional do Leste Asiático Tipo de estudo: Clinical_trials / Guideline / Risk_factors_studies / Systematic_reviews Limite: Humans País/Região como assunto: Asia Idioma: Zh Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Medicamentos de Ervas Chinesas / Medicina Tradicional do Leste Asiático Tipo de estudo: Clinical_trials / Guideline / Risk_factors_studies / Systematic_reviews Limite: Humans País/Região como assunto: Asia Idioma: Zh Ano de publicação: 2021 Tipo de documento: Article