Interleukin­8 released by cancer­associated fibroblasts attenuates the autophagy and promotes the migration of ovarian cancer cells.

Thongchot, Suyanee; Jamjuntra, Pranisa; Therasakvichya, Suwanit; Warnnissorn, Malee; Ferraresi, Alessandra; Thuwajit, Peti; Isidoro, Ciro; Thuwajit, Chanitra

Interleukin8 released by cancerassociated fibroblasts attenuates the autophagy and promotes the migration of ovarian cancer cells.

Thongchot, Suyanee; Jamjuntra, Pranisa; Therasakvichya, Suwanit; Warnnissorn, Malee; Ferraresi, Alessandra; Thuwajit, Peti; Isidoro, Ciro; Thuwajit, Chanitra.

Afiliação

Thongchot S; Department of Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
Jamjuntra P; Department of Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
Therasakvichya S; Department of Gynecology and Obstetrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
Warnnissorn M; Department of Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
Ferraresi A; Laboratory of Molecular Pathology, Department of Health Sciences, University of Eastern Piedmont 'A. Avogadro', I28100 Novara, Italy.
Thuwajit P; Department of Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
Isidoro C; Laboratory of Molecular Pathology, Department of Health Sciences, University of Eastern Piedmont 'A. Avogadro', I28100 Novara, Italy.
Thuwajit C; Department of Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.

Int J Oncol ; 58(5)2021 05.

Article em En | MEDLINE | ID: mdl-33649784

Assuntos

Fibroblastos Associados a Câncer/metabolismo; Interleucina-8/metabolismo; Neoplasias Ovarianas/metabolismo; Regulação para Cima; Autofagia/efeitos dos fármacos; Linhagem Celular Tumoral; Movimento Celular/efeitos dos fármacos; Proliferação de Células/efeitos dos fármacos; Meios de Cultivo Condicionados/metabolismo; Feminino; Regulação Neoplásica da Expressão Gênica/efeitos dos fármacos; Humanos; Interleucina-8/farmacologia; Metformina/farmacologia; Proteínas Associadas aos Microtúbulos/metabolismo; Sirolimo/farmacologia; Microambiente Tumoral; Regulação para Cima/efeitos dos fármacos

Palavras-chave

ovarian cancer; autophagy; IL8; cancerassociated fibroblast; migration; cytokines; tumor microenvironment

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Regulação para Cima / Interleucina-8 / Fibroblastos Associados a Câncer Tipo de estudo: Risk_factors_studies Limite: Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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