Rhinophototherapy, an alternative treatment of allergic rhinitis: Systematic review and meta-analysis.
Braz J Otorhinolaryngol
; 87(6): 742-752, 2021.
Article
em En
| MEDLINE
| ID: mdl-33663975
ABSTRACT
INTRODUCTION:
Allergic rhinitis is a chronic inflammatory disease of the nasal mucosa, mediated by immunoglobulin E, affecting 1 in 6 individuals. The treatment aims at attaining symptomatic control with minimal side effects, a requirement for new alternative therapies, including phototherapy, as it has an immunosuppressive and immunomodulatory effect.OBJECTIVE:
To identify the effectiveness of phototherapy in the treatment of allergic rhinitis through a meta-analysis.METHODS:
We searched Web of Science, Scielo, PubMed, SCOPUS, PEDro, and LILACS databases, using the terms "intranasal irradiation", "phototherapy" and "allergic rhinitis". The R software Metafor package was used for the meta-analysis and the effect size was calculated for each symptom individually.RESULTS:
All symptoms decreased considerably after phototherapy rhinorrhea (ESâ¢â¯=â¯-1.35; pâ¯<â¯0.0001; I2â¯=â¯91.84%), sneezing (ESâ¢â¯=â¯-1.24; pâ¯<⯠0.0001; I2â¯=â¯91.43%), nasal pruritus (ESâ¢â¯=â¯-1.10; pâ¯<â¯0.0001; I2â¯=â¯91.43%); nasal obstruction (ESâ¢â¯=â¯-1.11; pâ¯<â¯0.0001; I2â¯=â¯91.88%). The effects were more significant in perennial allergic rhinitis than in the seasonal type.CONCLUSION:
Considering the effect size and the statistical significance attained in our study, rhinophototherapy showed to be an effective treatment for reducing the nasal symptom scores triggered by AR.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Obstrução Nasal
/
Rinite Alérgica Perene
/
Rinite Alérgica
Tipo de estudo:
Prognostic_studies
/
Systematic_reviews
Limite:
Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article