Malignant vestibular schwannoma with intracerebral metastasis.
Br J Neurosurg
; 37(5): 1354-1357, 2023 Oct.
Article
em En
| MEDLINE
| ID: mdl-33686895
ABSTRACT
BACKGROUND:
Malignant change in vestibular schwannoma is rare and intracranial metastatic deposits have not been reported. CLINICAL PRESENTATION We report the case of a 64 year old woman with a benign vestibular schwannoma who underwent translabyrinthine excision in 1996 and Gamma Knife® radiosurgery (Elekta AB, Stockholm, Sweden) (GKRS) in 2006. She presents 10 years after GKRS with progressive neurological deterioration. Histopathologic analysis confirms a malignant peripheral nerve sheath tumour, WHO grade IV with subsequent metastatic spread to the left thalamus confirmed on biopsy.CONCLUSION:
We report a rare case of a vestibular schwannoma metastasizing with histological confirmation. It also reminds us of malignant conversion of a benign vestibular schwannoma following GKRS and subsequent aggressive behaviour, with poor prognosis.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neuroma Acústico
/
Radiocirurgia
Limite:
Female
/
Humans
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Middle aged
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article