Sepsis take-out: Inhibiting bacterial deliveries.
Immunity
; 54(3): 399-401, 2021 03 09.
Article
em En
| MEDLINE
| ID: mdl-33691128
ABSTRACT
Sepsis remains a deadly disease with limited treatment options. In this issue of Immunity, Tang et al. propose that heparin provides protection during gram-negative sepsis by dampening harmful CASP11-dependent signaling through inhibition of HMGB1- and heparanase-mediated cytosolic delivery of LPS.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecções por Bactérias Gram-Negativas
/
Sepse
/
Proteína HMGB1
Limite:
Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article