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Dual targeting of brain region-specific kinases potentiates neurological rescue in Spinocerebellar ataxia type 1.
Lee, Won-Seok; Lavery, Laura; Rousseaux, Maxime W C; Rutledge, Eric B; Jang, Youjin; Wan, Ying-Wooi; Wu, Sih-Rong; Kim, Wonho; Al-Ramahi, Ismael; Rath, Smruti; Adamski, Carolyn J; Bondar, Vitaliy V; Tewari, Ambika; Soleimani, Shirin; Mota, Samantha; Yalamanchili, Hari K; Orr, Harry T; Liu, Zhandong; Botas, Juan; Zoghbi, Huda Y.
Afiliação
  • Lee WS; Integrative Molecular and Biomedical Science Program, Baylor College of Medicine, Houston, TX, USA.
  • Lavery L; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
  • Rousseaux MWC; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX, USA.
  • Rutledge EB; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
  • Jang Y; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX, USA.
  • Wan YW; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
  • Wu SR; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX, USA.
  • Kim W; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX, USA.
  • Al-Ramahi I; Department of Pediatrics-Neurology, Baylor College of Medicine, Houston, TX, USA.
  • Rath S; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
  • Adamski CJ; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX, USA.
  • Bondar VV; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
  • Tewari A; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX, USA.
  • Soleimani S; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX, USA.
  • Mota S; Department of Neuroscience, Baylor College of Medicine, Houston, TX, USA.
  • Yalamanchili HK; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX, USA.
  • Orr HT; Howard Hughes Medical Institute, Houston, TX, USA.
  • Liu Z; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
  • Botas J; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX, USA.
  • Zoghbi HY; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
EMBO J ; 40(7): e106106, 2021 04 01.
Article em En | MEDLINE | ID: mdl-33709453
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Tronco Encefálico / Cerebelo / Ataxias Espinocerebelares / Proteínas Quinases S6 Ribossômicas 90-kDa / Proteínas de Ligação a DNA Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Tronco Encefálico / Cerebelo / Ataxias Espinocerebelares / Proteínas Quinases S6 Ribossômicas 90-kDa / Proteínas de Ligação a DNA Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article