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Design, Synthesis, and Evaluation of (2-Aminocyclopropyl)phenyl Derivatives as Novel Positron Emission Tomography Imaging Agents for Lysine-Specific Demethylase 1 in the Brain.
Hattori, Yasushi; Matsuda, Satoru; Baba, Rina; Matsumiya, Kouta; Iwasaki, Shinji; Constantinescu, Cristian C; Morley, Thomas J; Carroll, Vincent M; Papin, Caroline; Gouasmat, Alexandra; Alagille, David; Tamagnan, Gilles; Koike, Tatsuki.
Afiliação
  • Hattori Y; Research, Takeda Pharmaceutical Company Limited, 26-1 Muraoka-Higashi 2-Chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Matsuda S; Research, Takeda Pharmaceutical Company Limited, 26-1 Muraoka-Higashi 2-Chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Baba R; Research, Takeda Pharmaceutical Company Limited, 26-1 Muraoka-Higashi 2-Chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Matsumiya K; Research, Takeda Pharmaceutical Company Limited, 26-1 Muraoka-Higashi 2-Chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Iwasaki S; Research, Takeda Pharmaceutical Company Limited, 26-1 Muraoka-Higashi 2-Chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Constantinescu CC; Invicro LLC, 60 Temple Street, Suite 8A, New Haven, Connecticut 06518, United States.
  • Morley TJ; Invicro LLC, 60 Temple Street, Suite 8A, New Haven, Connecticut 06518, United States.
  • Carroll VM; Invicro LLC, 60 Temple Street, Suite 8A, New Haven, Connecticut 06518, United States.
  • Papin C; Invicro LLC, 60 Temple Street, Suite 8A, New Haven, Connecticut 06518, United States.
  • Gouasmat A; Invicro LLC, 60 Temple Street, Suite 8A, New Haven, Connecticut 06518, United States.
  • Alagille D; XingImaging LLC, 760 Temple Street, New Haven, Connecticut 06510, United States.
  • Tamagnan G; XingImaging LLC, 760 Temple Street, New Haven, Connecticut 06510, United States.
  • Koike T; Research, Takeda Pharmaceutical Company Limited, 26-1 Muraoka-Higashi 2-Chome, Fujisawa, Kanagawa 251-8555, Japan.
J Med Chem ; 64(7): 3780-3793, 2021 04 08.
Article em En | MEDLINE | ID: mdl-33729758
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Meios de Contraste / Ciclopropanos / Histona Desmetilases Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Meios de Contraste / Ciclopropanos / Histona Desmetilases Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article