Induced pluripotent stem cell (iPSC) line (ZZUNEUi009-A) from a healthy female individual.

Liu, Mengduan; Li, Xiaowei; Fu, Wanrong; Wang, Mengyu; Liu, Yangyang; Wang, Lu; Hu, Liang; Zhao, Xiaoyan; Dong, Jianzeng

Liu, Mengduan; Li, Xiaowei; Fu, Wanrong; Wang, Mengyu; Liu, Yangyang; Wang, Lu; Hu, Liang; Zhao, Xiaoyan; Dong, Jianzeng.

Afiliação

Liu M; Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China; Henan Key Laboratory of Hereditary Cardiovascular Diseases, Zhengzhou 450052, China.
Li X; Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China; Henan Key Laboratory of Hereditary Cardiovascular Diseases, Zhengzhou 450052, China.
Fu W; Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China; Henan Key Laboratory of Hereditary Cardiovascular Diseases, Zhengzhou 450052, China.
Wang M; Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China; Henan Key Laboratory of Hereditary Cardiovascular Diseases, Zhengzhou 450052, China.
Liu Y; Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China; Henan Key Laboratory of Hereditary Cardiovascular Diseases, Zhengzhou 450052, China.
Wang L; Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China; Henan Key Laboratory of Hereditary Cardiovascular Diseases, Zhengzhou 450052, China.
Hu L; Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China; Henan Key Laboratory of Hereditary Cardiovascular Diseases, Zhengzhou 450052, China.
Zhao X; Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China; Henan Key Laboratory of Hereditary Cardiovascular Diseases, Zhengzhou 450052, China.
Dong J; Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China; Henan Key Laboratory of Hereditary Cardiovascular Diseases, Zhengzhou 450052, China; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, National Clinical Research Cen

Stem Cell Res ; 53: 102275, 2021 05.

Article em En | MEDLINE | ID: mdl-33730648

ABSTRACT

ABSTRACT

Induced pluripotent stem cells (iPSCs) can be used to generate different types of somatic cells in vitro and are a useful tool for investigating drug and disease mechanisms. Here, we generated human induced pluripotent stem cell (iPSC) line ZZUNEUi009-A from an apparently healthy 28-year-old female by reprogramming peripheral blood mononuclear cells with non-integrating vector. The generated iPSCs was pluripotent, maintained a stable karyotype, and could generate the three layers (ectoderm, mesoderm, and endoderm) in vitro.

Assuntos

Células-Tronco Pluripotentes Induzidas; Adulto; Diferenciação Celular; Reprogramação Celular; Endoderma; Feminino; Humanos; Cariótipo; Leucócitos Mononucleares; Mesoderma

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Pluripotentes Induzidas Limite: Adult / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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