CircKDM4C upregulates P53 by sponging hsa-let-7b-5p to induce ferroptosis in acute myeloid leukemia.

Dong, Li-Hua; Huang, Jing-Jing; Zu, Peng; Liu, Jing; Gao, Xue; Du, Jian-Wei; Li, Yu-Fu

Dong, Li-Hua; Huang, Jing-Jing; Zu, Peng; Liu, Jing; Gao, Xue; Du, Jian-Wei; Li, Yu-Fu.

Afiliação

Dong LH; Department of Hematology, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, P.R. China.
Huang JJ; Department of Hematology, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, P.R. China.
Zu P; Department of Hematology, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, P.R. China.
Liu J; Department of Hematology, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, P.R. China.
Gao X; Department of Hematology, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, P.R. China.
Du JW; Department of Hematology, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, P.R. China.
Li YF; Department of Hematology, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, P.R. China.

Environ Toxicol ; 36(7): 1288-1302, 2021 Jul.

Article em En | MEDLINE | ID: mdl-33733556

Assuntos

Ferroptose; Leucemia Mieloide Aguda; MicroRNAs; Animais; Proliferação de Células; Humanos; Histona Desmetilases com o Domínio Jumonji; Leucemia Mieloide Aguda/genética; Camundongos; Camundongos Nus; Proteína Supressora de Tumor p53/genética

Palavras-chave

AML; CircKDM4C; P53; ferroptosis; hsa-let-7b-5p; migration and invasion; proliferation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / MicroRNAs / Ferroptose Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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