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Exploratory window-of-opportunity trial to investigate the tumor pharmacokinetics/pharmacodynamics of the IAP antagonist Debio 1143 in patients with head and neck cancer.
Gomez-Roca, Carlos; Even, Caroline; Le Tourneau, Christophe; Basté, Neus; Delord, Jean-Pierre; Sarini, Jerome; Vergez, Sebastien; Temam, Stephane; Hoffmann, Caroline; Rochaix, Philippe; Borcoman, Edith; Gavillet, Bruno; Rouits, Elisabeth; Ménétrey, Annick; Brichory, Franck; Purcea, Daniela; Vuagniaux, Gregoire; Zanna, Claudio.
Afiliação
  • Gomez-Roca C; Clinical Research Unit, Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France.
  • Even C; Institut Gustave-Roussy, Villejuif, France.
  • Le Tourneau C; Department of Drug Development and Innovation (D3i), Institut Curie, Paris and Saint-Cloud, France.
  • Basté N; Institut Gustave-Roussy, Villejuif, France.
  • Delord JP; Clinical Research Unit, Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France.
  • Sarini J; Surgery Department, Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France.
  • Vergez S; Surgery Department, Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France.
  • Temam S; Institut Gustave-Roussy, Villejuif, France.
  • Hoffmann C; Department of Drug Development and Innovation (D3i), Institut Curie, Paris and Saint-Cloud, France.
  • Rochaix P; Pathology Department, Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France.
  • Borcoman E; Department of Drug Development and Innovation (D3i), Institut Curie, Paris and Saint-Cloud, France.
  • Gavillet B; Debiopharm International S.A, Lausanne, Switzerland.
  • Rouits E; Debiopharm International S.A, Lausanne, Switzerland.
  • Ménétrey A; Debiopharm International S.A, Lausanne, Switzerland.
  • Brichory F; Debiopharm International S.A, Lausanne, Switzerland.
  • Purcea D; Debiopharm International S.A, Lausanne, Switzerland.
  • Vuagniaux G; Debiopharm International S.A, Lausanne, Switzerland.
  • Zanna C; Debiopharm International S.A, Lausanne, Switzerland.
Clin Transl Sci ; 15(1): 55-62, 2022 01.
Article em En | MEDLINE | ID: mdl-33742767
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Inibidoras de Apoptose / Microambiente Tumoral / Carcinoma de Células Escamosas de Cabeça e Pescoço Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Inibidoras de Apoptose / Microambiente Tumoral / Carcinoma de Células Escamosas de Cabeça e Pescoço Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article