Diosmetin, a novel transient receptor potential vanilloid 1 antagonist, alleviates the UVB radiation-induced skin inflammation in mice.

Camponogara, Camila; Brum, Evelyne S; Pegoraro, Natháli S; Brusco, Indiara; Brucker, Natália; Oliveira, Sara Marchesan

Camponogara, Camila; Brum, Evelyne S; Pegoraro, Natháli S; Brusco, Indiara; Brucker, Natália; Oliveira, Sara Marchesan.

Afiliação

Camponogara C; Laboratory Neurotoxicity and Psychopharmacology, Graduate Program in Biological Sciences: Toxicological Biochemistry, Center of Natural and Exact Sciences, Federal University of Santa Maria, Santa Maria, RS, Brazil.
Brum ES; Laboratory Neurotoxicity and Psychopharmacology, Graduate Program in Biological Sciences: Toxicological Biochemistry, Center of Natural and Exact Sciences, Federal University of Santa Maria, Santa Maria, RS, Brazil.
Pegoraro NS; Laboratory Neurotoxicity and Psychopharmacology, Graduate Program in Biological Sciences: Toxicological Biochemistry, Center of Natural and Exact Sciences, Federal University of Santa Maria, Santa Maria, RS, Brazil.
Brusco I; Laboratory Neurotoxicity and Psychopharmacology, Graduate Program in Biological Sciences: Toxicological Biochemistry, Center of Natural and Exact Sciences, Federal University of Santa Maria, Santa Maria, RS, Brazil.
Brucker N; Graduate Program in Pharmacology, Federal University of Santa Maria, Santa Maria, RS, Brazil.
Oliveira SM; Laboratory Neurotoxicity and Psychopharmacology, Graduate Program in Biological Sciences: Toxicological Biochemistry, Center of Natural and Exact Sciences, Federal University of Santa Maria, Santa Maria, RS, Brazil. saramarchesan@hotmail.com.

Inflammopharmacology ; 29(3): 879-895, 2021 Jun.

Article em En | MEDLINE | ID: mdl-33751333

Assuntos

Flavonoides/administração & dosagem; Pele/efeitos dos fármacos; Pele/efeitos da radiação; Queimadura Solar/tratamento farmacológico; Canais de Cátion TRPV/antagonistas & inibidores; Raios Ultravioleta/efeitos adversos; Animais; Relação Dose-Resposta a Droga; Inflamação/tratamento farmacológico; Inflamação/metabolismo; Masculino; Camundongos; Pele/metabolismo; Creme para a Pele/administração & dosagem; Queimadura Solar/metabolismo; Canais de Cátion TRPV/metabolismo

Palavras-chave

Diosmetin; Oxidative stress; Resiniferatoxin; Sunburn; TRP channels; Ultraviolet radiation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pele / Queimadura Solar / Raios Ultravioleta / Flavonoides / Canais de Cátion TRPV Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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