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Novel amino substituted tetracyclic imidazo[4,5-b]pyridine derivatives: Design, synthesis, antiproliferative activity and DNA/RNA binding study.
Loncar, Borka; Perin, Natasa; Mioc, Marija; Bocek, Ida; Grgic, Lea; Kralj, Marijeta; Tomic, Sanja; Stojkovic, Marijana Radic; Hranjec, Marijana.
Afiliação
  • Loncar B; Pliva d.o.o., odjel TAPI I&R, Unapredenje tehnoloskih procesa i Podrska proizvodnji, Croatia.
  • Perin N; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulicev trg 19, HR-10000, Zagreb, Croatia.
  • Mioc M; Division of Molecular Medicine, Ruder Boskovic Institute, Bijenicka cesta 54, HR-10000, Zagreb, Croatia.
  • Bocek I; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulicev trg 19, HR-10000, Zagreb, Croatia.
  • Grgic L; Ruder Boskovic Institute, Division of Organic Chemistry and Biochemistry, Bijenicka cesta 54, 10 000, Zagreb, Croatia.
  • Kralj M; Division of Molecular Medicine, Ruder Boskovic Institute, Bijenicka cesta 54, HR-10000, Zagreb, Croatia.
  • Tomic S; Ruder Boskovic Institute, Division of Organic Chemistry and Biochemistry, Bijenicka cesta 54, 10 000, Zagreb, Croatia.
  • Stojkovic MR; Ruder Boskovic Institute, Division of Organic Chemistry and Biochemistry, Bijenicka cesta 54, 10 000, Zagreb, Croatia. Electronic address: mradic@irb.hr.
  • Hranjec M; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulicev trg 19, HR-10000, Zagreb, Croatia. Electronic address: mhranjec@fkit.hr.
Eur J Med Chem ; 217: 113342, 2021 May 05.
Article em En | MEDLINE | ID: mdl-33751978
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridinas / DNA de Neoplasias / RNA Neoplásico / Desenho de Fármacos / Imidazóis / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridinas / DNA de Neoplasias / RNA Neoplásico / Desenho de Fármacos / Imidazóis / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article