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Gain-of-function factor H-related 5 protein impairs glomerular complement regulation resulting in kidney damage.
Malik, Talat H; Gitterman, Daniel P; Lavin, Deborah P; Lomax-Browne, Hannah J; Hiemeyer, E Christina; Moran, Linda B; Boroviak, Katharina; Cook, H Terence; Gilmore, Alyssa C; Mandwie, Mawj; Ahmad, Amina; Alexander, Ian E; Logan, Grant J; Marchbank, Kevin J; Bradley, Allan; Pickering, Matthew C.
Afiliação
  • Malik TH; Centre for Inflammatory Disease, Imperial College London, London W12 0NN, United Kingdom.
  • Gitterman DP; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, United Kingdom.
  • Lavin DP; Centre for Inflammatory Disease, Imperial College London, London W12 0NN, United Kingdom.
  • Lomax-Browne HJ; Centre for Inflammatory Disease, Imperial College London, London W12 0NN, United Kingdom.
  • Hiemeyer EC; Centre for Inflammatory Disease, Imperial College London, London W12 0NN, United Kingdom.
  • Moran LB; North West London Pathology, Imperial College Healthcare National Health Service Trust, London W6 8RF, United Kingdom.
  • Boroviak K; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, United Kingdom.
  • Cook HT; Centre for Inflammatory Disease, Imperial College London, London W12 0NN, United Kingdom.
  • Gilmore AC; Centre for Inflammatory Disease, Imperial College London, London W12 0NN, United Kingdom.
  • Mandwie M; Gene Therapy Research Unit, Children's Medical Research Institute and Sydney Children's Hospitals Network, The University of Sydney, NSW 2145 Westmead, Australia.
  • Ahmad A; Gene Therapy Research Unit, Children's Medical Research Institute and Sydney Children's Hospitals Network, The University of Sydney, NSW 2145 Westmead, Australia.
  • Alexander IE; Gene Therapy Research Unit, Children's Medical Research Institute and Sydney Children's Hospitals Network, The University of Sydney, NSW 2145 Westmead, Australia.
  • Logan GJ; Discipline of Child and Adolescent Health, Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, NSW 2145 Westmead, Australia.
  • Marchbank KJ; Gene Therapy Research Unit, Children's Medical Research Institute and Sydney Children's Hospitals Network, The University of Sydney, NSW 2145 Westmead, Australia.
  • Bradley A; Translational and Clinical Research Institute, The Medical School, Newcastle University, Framlington Place, Newcastle-upon-Tyne NE2 4HH, United Kingdom.
  • Pickering MC; National Renal Complement Therapeutics Centre, Newcastle-upon-Tyne NE1 4LP, United Kingdom.
Proc Natl Acad Sci U S A ; 118(13)2021 03 30.
Article em En | MEDLINE | ID: mdl-33753502
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas do Sistema Complemento / Complemento C3 / Mutação com Ganho de Função / Glomerulonefrite / Glomérulos Renais Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas do Sistema Complemento / Complemento C3 / Mutação com Ganho de Função / Glomerulonefrite / Glomérulos Renais Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article