Age-Related Changes of Material Mechanics and Bone Material Parameters of Rat Skulls.
Fa Yi Xue Za Zhi
; 37(1): 1-6, 2021 Feb.
Article
em En, Zh
| MEDLINE
| ID: mdl-33780176
ABSTRACT
ABSTRACT Objective To study the relationship between material mechanics and bone material parameters of rat skulls and their correlation with age by examination of the parameters. Methods Forty-eight healthy male SD rats were divided into 2, 4, 6, 8, 17, 26, 52 and 104 week groups according to their age. Each group had six rats. The right cranium was compressed by KD â
¡-0.2 microcomputer controlled electronic universal testing machine, and material mechanics parameters ï¼ultimate load, compression strength and compression modulusï¼ were measured, then the skull slices were cut off and scanned by Micro-CT system to detect bone material parameters ï¼skull thickness, bone mineral density, bone volume, and trabecular thicknessï¼. Results The differences in ultimate load, compression strength and compression modulus among all groups had statistical significance ï¼P<0.05ï¼, and were positively correlated with age within 26 weeks ï¼P<0.05ï¼. The differences in skull thickness, bone mineral density, bone volume and trabecular thickness among all groups had statistical significance ï¼P<0.05ï¼, and were positively correlated with age within 52 weeks ï¼P<0.05ï¼. All material mechanics parameters were positively correlated with bone material parameters ï¼P<0.05ï¼. Conclusion There is a positive correlation between bone material parameters ï¼skull thickness, bone mineral density, bone volume, trabecular thicknessï¼, material mechanics parameter ï¼skull ultimate load, compression strength, compression modulusï¼ and age in a certain range, which can be used to infer age.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Crânio
/
Densidade Óssea
Limite:
Animals
Idioma:
En
/
Zh
Ano de publicação:
2021
Tipo de documento:
Article