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Cyclin-dependent kinase inhibitor roscovitine attenuates liver inflammation and fibrosis by influencing initiating steps of liver injury.
Liu, Yanjun; Li, Jiacheng; Liao, Liping; Huang, Heming; Fan, Shijie; Fu, Rong; Huang, Jing; Shi, Cuicui; Yu, Liang; Chen, Kai-Xian; Zhang, Yuan-Yuan; Luo, Cheng; Li, Guang-Ming.
Afiliação
  • Liu Y; Department of Gastroenterology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, 1665 Kongjiang Road, Shanghai 200092, China.
  • Li J; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China.
  • Liao L; University of Chinese Academy of Sciences, 19 Yuquan Road, Beijing 100049, China.
  • Huang H; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China.
  • Fan S; University of Chinese Academy of Sciences, 19 Yuquan Road, Beijing 100049, China.
  • Fu R; Department of Gastroenterology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, 1665 Kongjiang Road, Shanghai 200092, China.
  • Huang J; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China.
  • Shi C; University of Chinese Academy of Sciences, 19 Yuquan Road, Beijing 100049, China.
  • Yu L; Department of Gastroenterology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, 1665 Kongjiang Road, Shanghai 200092, China.
  • Chen KX; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China.
  • Zhang YY; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China.
  • Luo C; University of Chinese Academy of Sciences, 19 Yuquan Road, Beijing 100049, China.
  • Li GM; Department of Gastroenterology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, 1665 Kongjiang Road, Shanghai 200092, China.
Clin Sci (Lond) ; 135(7): 925-941, 2021 04 16.
Article em En | MEDLINE | ID: mdl-33786590
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores de Proteínas Quinases / Roscovitina / Inflamação Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores de Proteínas Quinases / Roscovitina / Inflamação Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article