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A Clinical-Stage Cysteine Protease Inhibitor blocks SARS-CoV-2 Infection of Human and Monkey Cells.
Mellott, Drake M; Tseng, Chien-Te; Drelich, Aleksandra; Fajtová, Pavla; Chenna, Bala C; Kostomiris, Demetrios H; Hsu, Jason; Zhu, Jiyun; Taylor, Zane W; Kocurek, Klaudia I; Tat, Vivian; Katzfuss, Ardala; Li, Linfeng; Giardini, Miriam A; Skinner, Danielle; Hirata, Ken; Yoon, Michael C; Beck, Sungjun; Carlin, Aaron F; Clark, Alex E; Beretta, Laura; Maneval, Daniel; Hook, Vivian; Frueh, Felix; Hurst, Brett L; Wang, Hong; Raushel, Frank M; O'Donoghue, Anthony J; de Siqueira-Neto, Jair Lage; Meek, Thomas D; McKerrow, James H.
Afiliação
  • Tseng CT; Department of Microbiology and Immunology, University of Texas, Medical Branch, 3000 University Boulevard, Galveston, Texas 77755-1001, United States.
  • Drelich A; Department of Microbiology and Immunology, University of Texas, Medical Branch, 3000 University Boulevard, Galveston, Texas 77755-1001, United States.
  • Fajtová P; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California 92093, United States.
  • Chenna BC; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 16610 Prague, Czech Republic.
  • Zhu J; Department of Microbiology and Immunology, University of Texas, Medical Branch, 3000 University Boulevard, Galveston, Texas 77755-1001, United States.
  • Katzfuss A; Department of Microbiology and Immunology, University of Texas, Medical Branch, 3000 University Boulevard, Galveston, Texas 77755-1001, United States.
  • Skinner D; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California 92093, United States.
  • Hirata K; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California 92093, United States.
  • Yoon MC; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California 92093, United States.
  • Beck S; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California 92093, United States.
  • Carlin AF; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California 92093, United States.
  • Clark AE; Department of Medicine, Division of Infectious Diseases and Global Public Health, University of California San Diego, La Jolla, California 92037, United States.
  • Beretta L; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California 92093, United States.
  • Maneval D; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California 92093, United States.
  • Frueh F; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California 92093, United States.
  • de Siqueira-Neto JL; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California 92093, United States.
  • Meek TD; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California 92093, United States.
ACS Chem Biol ; 16(4): 642-650, 2021 04 16.
Article em En | MEDLINE | ID: mdl-33787221
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Fenilalanina / Piperazinas / Compostos de Tosil / Inibidores de Cisteína Proteinase / SARS-CoV-2 Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Fenilalanina / Piperazinas / Compostos de Tosil / Inibidores de Cisteína Proteinase / SARS-CoV-2 Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article