AASRA: an anchor alignment-based small RNA annotation pipeline.
Biol Reprod
; 105(1): 267-277, 2021 07 02.
Article
em En
| MEDLINE
| ID: mdl-33787835
ABSTRACT
Small noncoding RNAs deep sequencing (sncRNA-Seq) has become a routine for sncRNA detection and quantification. However, the software packages currently available for sncRNA annotation can neither recognize sncRNA variants in the sequencing reads, nor annotate all known sncRNA simultaneously. Here, we report a novel anchor alignment-based small RNA annotation (AASRA) software package (https//github.com/biogramming/AASRA). AASRA represents an all-in-one sncRNA annotation pipeline, which allows for high-speed, simultaneous annotation of all known sncRNA species with the capability to distinguish mature from precursor microRNAs, and to identify novel sncRNA variants in the sncRNA-Seq sequencing reads.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Software
/
MicroRNAs
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Anotação de Sequência Molecular
/
Camundongos
Limite:
Animals
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article