Recent trends in drugs of abuse metabolism studies for mass spectrometry-based analytical screening procedures.

Wagmann, Lea; Gampfer, Tanja M; Meyer, Markus R

Wagmann, Lea; Gampfer, Tanja M; Meyer, Markus R.

Afiliação

Wagmann L; Department of Experimental and Clinical Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS), Saarland University, Kirrberger Straße Building 46, 66421, Homburg, Germany. lea.wagmann@uks.eu.
Gampfer TM; Department of Experimental and Clinical Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS), Saarland University, Kirrberger Straße Building 46, 66421, Homburg, Germany.
Meyer MR; Department of Experimental and Clinical Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS), Saarland University, Kirrberger Straße Building 46, 66421, Homburg, Germany.

Anal Bioanal Chem ; 413(22): 5551-5559, 2021 Sep.

Article em En | MEDLINE | ID: mdl-33792746

Assuntos

Drogas Ilícitas/metabolismo; Espectrometria de Massas/métodos; Ativação Metabólica; Animais; Sistema Enzimático do Citocromo P-450/metabolismo; Hepatócitos/enzimologia; Hepatócitos/metabolismo; Humanos; Microssomos Hepáticos/metabolismo

Palavras-chave

In vitro toxicology; In vivo toxicology; Mass spectrometry; Metabolism; New psychoactive substances; Screening

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Espectrometria de Massas / Drogas Ilícitas Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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