Organ-on-chip to investigate host-pathogens interactions.
Cell Microbiol
; 23(7): e13336, 2021 07.
Article
em En
| MEDLINE
| ID: mdl-33798273
ABSTRACT
Infectious diseases remain the subject of intense research. This topic reaches a new era towards the study of host-pathogen interactions mechanisms at the tissue scale. The past few years have hence witnessed the emergence of new methods. Among them, organ-on-chip, which combines biomaterial technology, microfluidic and tissue engineering to recreate the organ physiology is very promising. This review summarises how this technology recapitulates the architecture, the mechanical stimulation and the interface of a tissue and how this particular microenvironment is critical to study host-pathogen interactions.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Engenharia Tecidual
/
Microfluídica
/
Interações Hospedeiro-Patógeno
/
Infecções
Limite:
Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article