Single-Cell Sequencing Confirms Transcripts and V<sub>H</sub>DJ<sub>H</sub> Rearrangements of Immunoglobulin Genes in Human Podocytes.

Deng, Zhenling; Yan, Huige; Shi, Zhan; Tian, Xinyu; Cui, Zhuan; Sun, Yingchun; Wang, Song; Zheng, Danxia; Qiu, Xiaoyan; Wang, Yue

Single-Cell Sequencing Confirms Transcripts and V_HDJ_H Rearrangements of Immunoglobulin Genes in Human Podocytes.

Deng, Zhenling; Yan, Huige; Shi, Zhan; Tian, Xinyu; Cui, Zhuan; Sun, Yingchun; Wang, Song; Zheng, Danxia; Qiu, Xiaoyan; Wang, Yue.

Afiliação

Deng Z; Department of Nephrology, Peking University Third Hospital, Beijing 100191, China.
Yan H; Department of Immunology, School of Basic Medical Sciences, Peking University, Beijing 100191, China.
Shi Z; Department of Immunology, School of Basic Medical Sciences, Peking University, Beijing 100191, China.
Tian X; Department of Nephrology, Peking University Third Hospital, Beijing 100191, China.
Cui Z; Department of Nephrology, Peking University Third Hospital, Beijing 100191, China.
Sun Y; Department of Nephrology, Peking University Third Hospital, Beijing 100191, China.
Wang S; Department of Nephrology, Peking University Third Hospital, Beijing 100191, China.
Zheng D; Department of Nephrology, Peking University Third Hospital, Beijing 100191, China.
Qiu X; Department of Immunology, School of Basic Medical Sciences, Peking University, Beijing 100191, China.
Wang Y; Department of Nephrology, Peking University Third Hospital, Beijing 100191, China.

Genes (Basel) ; 12(4)2021 03 25.

Article em En | MEDLINE | ID: mdl-33806147

Assuntos

Rearranjo Gênico; Cadeias J de Imunoglobulina/genética; Região Variável de Imunoglobulina/genética; Cadeias delta de Imunoglobulina/genética; Nefropatias/genética; Podócitos/patologia; Análise de Célula Única/métodos; Sequência de Bases; Estudos de Casos e Controles; Humanos; Nefropatias/patologia; Podócitos/metabolismo; Homologia de Sequência do Ácido Nucleico

Palavras-chave

VHDJH rearrangement; gene transcription; immunoglobulins; podocyte; single-cell RNA sequencing

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Região Variável de Imunoglobulina / Rearranjo Gênico / Cadeias delta de Imunoglobulina / Cadeias J de Imunoglobulina / Podócitos / Análise de Célula Única / Nefropatias Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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