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Non-Coding RNAs as Prognostic Markers for Endometrial Cancer.
Piergentili, Roberto; Zaami, Simona; Cavaliere, Anna Franca; Signore, Fabrizio; Scambia, Giovanni; Mattei, Alberto; Marinelli, Enrico; Gulia, Caterina; Perelli, Federica.
Afiliação
  • Piergentili R; Institute of Molecular Biology and Pathology, Italian National Research Council (CNR-IBPM), 00185 Rome, Italy.
  • Zaami S; Department of Anatomical, Histological, Forensic and Orthopedic Sciences, "Sapienza" University of Rome, Viale Regina Elena 336, 00161 Rome, Italy.
  • Cavaliere AF; Gynecology and Obstetric Department, Azienda USL Toscana Centro, Santo Stefano Hospital, 59100 Prato, Italy.
  • Signore F; Obstetrics and Gynecology Department, USL Roma2, Sant'Eugenio Hospital, 00144 Rome, Italy.
  • Scambia G; Fondazione Policlinico Universitario A. Gemelli IRCCS, Gynecologic Oncology Unit, 00168 Rome, Italy.
  • Mattei A; Universita' Cattolica Del Sacro Cuore, 00168 Rome, Italy.
  • Marinelli E; Gynecology and Obstetric Department, Azienda USL Toscana Centro, Santa Maria Annunziata Hospital, 50012 Florence, Italy.
  • Gulia C; Unit of Forensic Toxicology (UoFT), Department of Anatomical, Histological, Forensic and Orthopedic Sciences, Sapienza University, 00161 Rome, Italy.
  • Perelli F; Department of Urology, Misericordia Hospital, 58100 Grosseto, Italy.
Int J Mol Sci ; 22(6)2021 Mar 19.
Article em En | MEDLINE | ID: mdl-33808791
ABSTRACT
Endometrial cancer (EC) has been classified over the years, for prognostic and therapeutic purposes. In recent years, classification systems have been emerging not only based on EC clinical and pathological characteristics but also on its genetic and epigenetic features. Noncoding RNAs (ncRNAs) are emerging as promising markers in several cancer types, including EC, for which their prognostic value is currently under investigation and will likely integrate the present prognostic tools based on protein coding genes. This review aims to underline the importance of the genetic and epigenetic events in the EC tumorigenesis, by expounding upon the prognostic role of ncRNAs.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biomarcadores Tumorais / Neoplasias do Endométrio / RNA não Traduzido Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biomarcadores Tumorais / Neoplasias do Endométrio / RNA não Traduzido Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article