The amphetamine challenge test in patients with borderline disorder.
Am J Psychiatry
; 145(7): 809-14, 1988 Jul.
Article
em En
| MEDLINE
| ID: mdl-3381923
ABSTRACT
The authors used amphetamine as a psychopharmacological probe to investigate the hypothesis that patients with borderline personality disorder are prone to psychosis following ingestion of a dopamine agonist. Sixteen patients with borderline personality disorder participated in the study. Significant increases in the mean total Brief Psychiatric Rating Scale scores and in activation and thought disturbance factors after amphetamine administration were noted in the sample. Patients with diagnoses of both schizotypal and borderline personality disorders worsened transiently with amphetamine administration, but patients with only the borderline diagnosis improved. These results indicate the usefulness of pharmacological probes to further understand DSM-III axis II disorders.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transtornos da Personalidade
/
Transtorno da Personalidade Borderline
/
Dextroanfetamina
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Ano de publicação:
1988
Tipo de documento:
Article