Circadian clock modulating small molecules repurposing as inhibitors of SARS-CoV-2 M<sup>pro</sup> for pharmacological interventions in COVID-19 pandemic.

Sultan, Armiya; Ali, Rafat; Sultan, Tahira; Ali, Sher; Khan, Nida Jamil; Parganiha, Arti

Circadian clock modulating small molecules repurposing as inhibitors of SARS-CoV-2 M^pro for pharmacological interventions in COVID-19 pandemic.

Sultan, Armiya; Ali, Rafat; Sultan, Tahira; Ali, Sher; Khan, Nida Jamil; Parganiha, Arti.

Afiliação

Sultan A; Functional Genomics Laboratory, Center for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia (A Central University), New Delhi, India.
Ali R; Department of Biosciences, Jamia Millia Islamia (A Central University), New Delhi, India.
Sultan T; Chronobiology and Animal Behaviour Laboratory, School of Studies in Life Sciences, Pt. Ravishankar Shukla University, Raipur, India.
Ali S; Department of Biosciences, Jamia Millia Islamia (A Central University), New Delhi, India.
Khan NJ; Department of Biochemistry, University of Kashmir, Srinagar, India.
Parganiha A; Department of Life Sciences, Sharda University, Greater Noida, India.

Chronobiol Int ; 38(7): 971-985, 2021 07.

Article em En | MEDLINE | ID: mdl-33820462

Assuntos

COVID-19; Relógios Circadianos; Antivirais/farmacologia; Ritmo Circadiano; Reposicionamento de Medicamentos; Humanos; Simulação de Acoplamento Molecular; Pandemias; Inibidores de Proteases; SARS-CoV-2

Palavras-chave

COVID-19; Circadian clock-modulating molecules; SARS-CoV-2 Mpro; SRT2183; inhibitors; main protease; pandemic; targeted therapy

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Relógios Circadianos / COVID-19 Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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