Skeletal Maturation in Patients With Cleft Lip and/or Palate: A Systematic Review.
Cleft Palate Craniofac J
; 59(3): 307-319, 2022 Mar.
Article
em En
| MEDLINE
| ID: mdl-33827285
ABSTRACT
OBJECTIVE:
The objective of this systematic review was to evaluate the evidence regarding skeletal maturation in patients with cleft lip and/or palate (CL/P) and to investigate whether the skeletal maturation is delayed in these patients.DESIGN:
Systematic review.METHODS:
Electronic and manual searches of scientific literature were conducted in 4 databases (MEDLINE, Embase, Cochrane Library, and Web of Science). Cohort studies that compared the skeletal maturation of patients with CL/P with that of children without CL/P were eligible for inclusion. The quality of included cohort studies was assessed using the Newcastle-Ottawa Scale. PATIENTS ANDPARTICIPANTS:
Patients of any sex and ethnicity with CL/P and children without CL/P were included in this systematic review. MAIN OUTCOMEMEASURES:
Difference in skeletal maturation between patients with CL/P and patients without CL/P.RESULTS:
Thirteen retrospective cohort studies were included in this systematic review. Ten studies were considered of high quality and 3 were considered of general quality. The results of the included studies comparing skeletal maturation of patients with CL/P and children without CL/P were heterogeneous.CONCLUSION:
Heterogeneity of skeletal maturation assessment methods, chronological age, sex, cleft type, and race may influence the final results of clinical studies on skeletal maturation in patients with CL/P. Overall, there is limited evidence to determine whether the skeletal maturation level of patients with CL/P is delayed compared to that of normal children. Further studies are needed to determine the skeletal maturation patterns in patients with CL/P.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fenda Labial
/
Fissura Palatina
Tipo de estudo:
Guideline
/
Observational_studies
/
Systematic_reviews
Limite:
Child
/
Humans
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article