How do antiporters exchange substrates across the cell membrane? An atomic-level description of the complete exchange cycle in NarK.

Feng, Jiangyan; Selvam, Balaji; Shukla, Diwakar

Feng, Jiangyan; Selvam, Balaji; Shukla, Diwakar.

Afiliação

Feng J; Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Selvam B; Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Shukla D; Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA; Department of Plant Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA; Center for Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA; NIH Center for Macromolecular Modeling and Bioinformatics, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA; Beckman Institute for Advanced Science and

Structure ; 29(8): 922-933.e3, 2021 08 05.

Article em En | MEDLINE | ID: mdl-33836147

Assuntos

Escherichia coli/metabolismo; Transportadores de Nitrato/química; Transportadores de Nitrato/metabolismo; Sítios de Ligação; Membrana Celular/metabolismo; Modelos Moleculares; Simulação de Dinâmica Molecular; Conformação Proteica

Palavras-chave

Markov state models; antiporter; membrane transporter; molecular dynamics; nitrate/nitrite exchanger

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Escherichia coli / Transportadores de Nitrato Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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