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Antibodies to the SARS-CoV-2 receptor-binding domain that maximize breadth and resistance to viral escape.
Starr, Tyler N; Czudnochowski, Nadine; Zatta, Fabrizia; Park, Young-Jun; Liu, Zhuoming; Addetia, Amin; Pinto, Dora; Beltramello, Martina; Hernandez, Patrick; Greaney, Allison J; Marzi, Roberta; Glass, William G; Zhang, Ivy; Dingens, Adam S; Bowen, John E; Wojcechowskyj, Jason A; De Marco, Anna; Rosen, Laura E; Zhou, Jiayi; Montiel-Ruiz, Martin; Kaiser, Hannah; Tucker, Heather; Housley, Michael P; di Iulio, Julia; Lombardo, Gloria; Agostini, Maria; Sprugasci, Nicole; Culap, Katja; Jaconi, Stefano; Meury, Marcel; Dellota, Exequiel; Cameroni, Elisabetta; Croll, Tristan I; Nix, Jay C; Havenar-Daughton, Colin; Telenti, Amalio; Lempp, Florian A; Pizzuto, Matteo S; Chodera, John D; Hebner, Christy M; Whelan, Sean P J; Virgin, Herbert W; Veesler, David; Corti, Davide; Bloom, Jesse D; Snell, Gyorgy.
Afiliação
  • Starr TN; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Czudnochowski N; Vir Biotechnology, San Francisco, CA 94158, USA.
  • Zatta F; Humabs BioMed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
  • Park YJ; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
  • Liu Z; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Addetia A; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Pinto D; Humabs BioMed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
  • Beltramello M; Humabs BioMed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
  • Hernandez P; Vir Biotechnology, San Francisco, CA 94158, USA.
  • Greaney AJ; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Marzi R; Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA.
  • Glass WG; Humabs BioMed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
  • Zhang I; Computational and Systems Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Dingens AS; Computational and Systems Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Bowen JE; Tri-Institutional PhD Program in Computational Biology and Medicine, Weill Cornell Graduate School of Medical Sciences, New York, NY 10065, USA.
  • Wojcechowskyj JA; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • De Marco A; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
  • Rosen LE; Vir Biotechnology, San Francisco, CA 94158, USA.
  • Zhou J; Humabs BioMed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
  • Montiel-Ruiz M; Vir Biotechnology, San Francisco, CA 94158, USA.
  • Kaiser H; Vir Biotechnology, San Francisco, CA 94158, USA.
  • Tucker H; Vir Biotechnology, San Francisco, CA 94158, USA.
  • Housley MP; Vir Biotechnology, San Francisco, CA 94158, USA.
  • di Iulio J; Vir Biotechnology, San Francisco, CA 94158, USA.
  • Lombardo G; Vir Biotechnology, San Francisco, CA 94158, USA.
  • Agostini M; Vir Biotechnology, San Francisco, CA 94158, USA.
  • Sprugasci N; Humabs BioMed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
  • Culap K; Vir Biotechnology, San Francisco, CA 94158, USA.
  • Jaconi S; Humabs BioMed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
  • Meury M; Humabs BioMed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
  • Dellota E; Humabs BioMed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
  • Cameroni E; Vir Biotechnology, San Francisco, CA 94158, USA.
  • Croll TI; Vir Biotechnology, San Francisco, CA 94158, USA.
  • Nix JC; Humabs BioMed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
  • Havenar-Daughton C; Cambridge Institute for Medical Research, Department of Haematology, University of Cambridge, Cambridge, CB2 0XY, UK.
  • Telenti A; Molecular Biology Consortium, Advanced Light Source, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
  • Lempp FA; Vir Biotechnology, San Francisco, CA 94158, USA.
  • Pizzuto MS; Vir Biotechnology, San Francisco, CA 94158, USA.
  • Chodera JD; Vir Biotechnology, San Francisco, CA 94158, USA.
  • Hebner CM; Humabs BioMed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
  • Whelan SPJ; Computational and Systems Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Virgin HW; Vir Biotechnology, San Francisco, CA 94158, USA.
  • Veesler D; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Corti D; Vir Biotechnology, San Francisco, CA 94158, USA.
  • Bloom JD; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA.
  • Snell G; Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX 75390, USA.
bioRxiv ; 2021 Apr 08.
Article em En | MEDLINE | ID: mdl-33851154

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article