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Synthetic repertoires derived from convalescent COVID-19 patients enable discovery of SARS-CoV-2 neutralizing antibodies and a novel quaternary binding modality.
Goike, Jule; Hsieh, Ching-Lin; Horton, Andrew; Gardner, Elizabeth C; Bartzoka, Foteini; Wang, Nianshuang; Javanmardi, Kamyab; Herbert, Andrew; Abbassi, Shawn; Renberg, Rebecca; Johanson, Michael J; Cardona, Jose A; Segall-Shapiro, Thomas; Zhou, Ling; Nissly, Ruth H; Gontu, Abhinay; Byrom, Michelle; Maranhao, Andre C; Battenhouse, Anna M; Gejji, Varun; Soto-Sierra, Laura; Foster, Emma R; Woodard, Susan L; Nikolov, Zivko L; Lavinder, Jason; Voss, Will N; Annapareddy, Ankur; Ippolito, Gregory C; Ellington, Andrew D; Marcotte, Edward M; Finkelstein, Ilya J; Hughes, Randall A; Musser, James M; Kuchipudi, Suresh V; Kapur, Vivek; Georgiou, George; Dye, John M; Boutz, Daniel R; McLellan, Jason S; Gollihar, Jimmy D.
Afiliação
  • Goike J; Center for Systems and Synthetic Biology, Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, USA.
  • Hsieh CL; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, USA.
  • Horton A; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, USA.
  • Gardner EC; Center for Systems and Synthetic Biology, Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, USA.
  • Bartzoka F; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, USA.
  • Wang N; Center for Systems and Synthetic Biology, Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, USA.
  • Javanmardi K; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, USA.
  • Herbert A; Center for Systems and Synthetic Biology, Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, USA.
  • Abbassi S; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, USA.
  • Renberg R; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, USA.
  • Johanson MJ; Center for Systems and Synthetic Biology, Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, USA.
  • Cardona JA; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, USA.
  • Segall-Shapiro T; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, MD, USA.
  • Zhou L; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, MD, USA.
  • Nissly RH; CCDC Army Research Laboratory, Biotechnology Branch, Adelphi, MD, USA.
  • Gontu A; National Center for Therapeutics Manufacturing, Texas A&M University, College Station, TX, USA.
  • Byrom M; Center for Systems and Synthetic Biology, Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, USA.
  • Maranhao AC; CCDC Army Research Laboratory-South, Austin, TX, USA.
  • Battenhouse AM; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, USA.
  • Gejji V; Department of Veterinary and Biomedical Science and Animal Diagnostic Laboratory, The Pennsylvania State University, University Park, Pennsylvania, USA.
  • Soto-Sierra L; Department of Veterinary and Biomedical Science and Animal Diagnostic Laboratory, The Pennsylvania State University, University Park, Pennsylvania, USA.
  • Foster ER; Center for Systems and Synthetic Biology, Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, USA.
  • Woodard SL; Center for Systems and Synthetic Biology, Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, USA.
  • Nikolov ZL; Center for Systems and Synthetic Biology, Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, USA.
  • Lavinder J; National Center for Therapeutics Manufacturing, Texas A&M University, College Station, TX, USA.
  • Voss WN; National Center for Therapeutics Manufacturing, Texas A&M University, College Station, TX, USA.
  • Annapareddy A; Department of Agricultural and Biological Engineering, Texas A&M University, College Station, TX, USA.
  • Ippolito GC; National Center for Therapeutics Manufacturing, Texas A&M University, College Station, TX, USA.
  • Ellington AD; Department of Agricultural and Biological Engineering, Texas A&M University, College Station, TX, USA.
  • Marcotte EM; National Center for Therapeutics Manufacturing, Texas A&M University, College Station, TX, USA.
  • Finkelstein IJ; National Center for Therapeutics Manufacturing, Texas A&M University, College Station, TX, USA.
  • Hughes RA; Department of Agricultural and Biological Engineering, Texas A&M University, College Station, TX, USA.
  • Musser JM; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, USA.
  • Kuchipudi SV; Department of Chemical Engineering, The University of Texas at Austin, Austin, TX, USA.
  • Kapur V; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, USA.
  • Georgiou G; Center for Systems and Synthetic Biology, Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, USA.
  • Dye JM; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, USA.
  • Boutz DR; CCDC Army Research Laboratory-South, Austin, TX, USA.
  • McLellan JS; Center for Systems and Synthetic Biology, Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, USA.
  • Gollihar JD; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, USA.
bioRxiv ; 2021 Apr 09.
Article em En | MEDLINE | ID: mdl-33851158
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article