Your browser doesn't support javascript.
loading
Discovery of the Soluble Guanylate Cyclase Activator Runcaciguat (BAY 1101042).
Hahn, Michael G; Lampe, Thomas; El Sheikh, Sherif; Griebenow, Nils; Woltering, Elisabeth; Schlemmer, Karl-Heinz; Dietz, Lisa; Gerisch, Michael; Wunder, Frank; Becker-Pelster, Eva-Maria; Mondritzki, Thomas; Tinel, Hanna; Knorr, Andreas; Kern, Armin; Lang, Dieter; Hueser, Joerg; Schomber, Tibor; Benardeau, Agnes; Eitner, Frank; Truebel, Hubert; Mittendorf, Joachim; Kumar, Vijay; van den Akker, Focco; Schaefer, Martina; Geiss, Volker; Sandner, Peter; Stasch, Johannes-Peter.
Afiliação
  • Hahn MG; Research and Development, Bayer AG, Pharmaceuticals, Aprather Weg 18a, 42113 Wuppertal, Germany.
  • Lampe T; Research and Development, Bayer AG, Pharmaceuticals, Aprather Weg 18a, 42113 Wuppertal, Germany.
  • El Sheikh S; Research and Development, Bayer AG, Pharmaceuticals, Aprather Weg 18a, 42113 Wuppertal, Germany.
  • Griebenow N; Research and Development, Bayer AG, Pharmaceuticals, Aprather Weg 18a, 42113 Wuppertal, Germany.
  • Woltering E; Research and Development, Bayer AG, Pharmaceuticals, Aprather Weg 18a, 42113 Wuppertal, Germany.
  • Schlemmer KH; Research and Development, Bayer AG, Pharmaceuticals, Aprather Weg 18a, 42113 Wuppertal, Germany.
  • Dietz L; Research and Development, Bayer AG, Pharmaceuticals, Aprather Weg 18a, 42113 Wuppertal, Germany.
  • Gerisch M; Research and Development, Bayer AG, Pharmaceuticals, Aprather Weg 18a, 42113 Wuppertal, Germany.
  • Wunder F; Research and Development, Bayer AG, Pharmaceuticals, Aprather Weg 18a, 42113 Wuppertal, Germany.
  • Becker-Pelster EM; Research and Development, Bayer AG, Pharmaceuticals, Aprather Weg 18a, 42113 Wuppertal, Germany.
  • Mondritzki T; Research and Development, Bayer AG, Pharmaceuticals, Aprather Weg 18a, 42113 Wuppertal, Germany.
  • Tinel H; University of Witten/Herdecke, 58455 Witten, Germany.
  • Knorr A; Research and Development, Bayer AG, Pharmaceuticals, Aprather Weg 18a, 42113 Wuppertal, Germany.
  • Kern A; Research and Development, Bayer AG, Pharmaceuticals, Aprather Weg 18a, 42113 Wuppertal, Germany.
  • Lang D; Research and Development, Bayer AG, Pharmaceuticals, Aprather Weg 18a, 42113 Wuppertal, Germany.
  • Hueser J; Research and Development, Bayer AG, Pharmaceuticals, Aprather Weg 18a, 42113 Wuppertal, Germany.
  • Schomber T; Research and Development, Bayer AG, Pharmaceuticals, Aprather Weg 18a, 42113 Wuppertal, Germany.
  • Benardeau A; Research and Development, Bayer AG, Pharmaceuticals, Aprather Weg 18a, 42113 Wuppertal, Germany.
  • Eitner F; Research and Development, Bayer AG, Pharmaceuticals, Aprather Weg 18a, 42113 Wuppertal, Germany.
  • Truebel H; Research and Development, Bayer AG, Pharmaceuticals, Aprather Weg 18a, 42113 Wuppertal, Germany.
  • Mittendorf J; Division of Nephrology and Clinical Immunology, RWTH Aachen University, 52074 Aachen, Germany.
  • Kumar V; Research and Development, Bayer AG, Pharmaceuticals, Aprather Weg 18a, 42113 Wuppertal, Germany.
  • van den Akker F; University of Witten/Herdecke, 58455 Witten, Germany.
  • Schaefer M; Research and Development, Bayer AG, Pharmaceuticals, Aprather Weg 18a, 42113 Wuppertal, Germany.
  • Geiss V; Department of Biochemistry, Case Western Reserve University, 44106 Cleveland, Ohio, United States.
  • Sandner P; Department of Biochemistry, Case Western Reserve University, 44106 Cleveland, Ohio, United States.
  • Stasch JP; Lead Discovery-Structural Biology, Nuvisan ICB GmbH, 13353 Berlin, Germany.
J Med Chem ; 64(9): 5323-5344, 2021 05 13.
Article em En | MEDLINE | ID: mdl-33872507
Assuntos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Ativadores de Enzimas / Guanilil Ciclase Solúvel Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Ativadores de Enzimas / Guanilil Ciclase Solúvel Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article