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An orthogonal methods assessment of topical drug concentrations in skin and the impact for risk assessment in the viable epidermis.
Hollingshead, Brett D; Tomlinson, Lindsay; Finley, Jim; Doshna, Colleen; Ritenour, Casey; Barricklow, Jason; Oppenheimer, Stacey R; O'Neil, Shawn P; Moore, Jessica L; Patterson, Nathan Heath; Nicholson, Sarah P; Norris, Jeremy L; Caprioli, Richard M; Beaumont, Kevin; King-Ahmad, Amanda J; Vispute, Saurabh; Cook, Jon C; Radi, Zaher; Schuler, Maik.
Afiliação
  • Hollingshead BD; Pfizer Drug Safety Research and Development, 1 Portland Street, Cambridge, MA, 02139, USA. Electronic address: brett.d.hollingshead@pfizer.com.
  • Tomlinson L; Pfizer Drug Safety Research and Development, 1 Portland Street, Cambridge, MA, 02139, USA.
  • Finley J; Pfizer Drug Safety Research and Development, Eastern Point Road, Groton, CT, 06340, USA.
  • Doshna C; Pfizer Drug Safety Research and Development, Eastern Point Road, Groton, CT, 06340, USA.
  • Ritenour C; Pfizer Drug Safety Research and Development, Eastern Point Road, Groton, CT, 06340, USA.
  • Barricklow J; Pfizer Pharmacokinetics, Dynamics and Metabolism, Eastern Point Road, Groton, CT, 06340, USA.
  • Oppenheimer SR; Pfizer Early Clinical Development, 610 Main Street, Cambridge, MA, 02139, USA.
  • O'Neil SP; Pfizer Drug Safety Research and Development, 1 Portland Street, Cambridge, MA, 02139, USA.
  • Moore JL; Frontier Diagnostics, 345 Hill Ave, Nashville, TN, 37210, USA.
  • Patterson NH; Frontier Diagnostics, 345 Hill Ave, Nashville, TN, 37210, USA.
  • Nicholson SP; Frontier Diagnostics, 345 Hill Ave, Nashville, TN, 37210, USA.
  • Norris JL; Frontier Diagnostics, 345 Hill Ave, Nashville, TN, 37210, USA.
  • Caprioli RM; Frontier Diagnostics, 345 Hill Ave, Nashville, TN, 37210, USA.
  • Beaumont K; Pfizer Pharmacokinetics, Dynamics and Metabolism, 1 Portland Street, Cambridge, MA, 02139, USA.
  • King-Ahmad AJ; Pfizer Pharmacokinetics, Dynamics and Metabolism, Eastern Point Road, Groton, CT, 06340, USA.
  • Vispute S; Pfizer Drug Safety Research and Development, Eastern Point Road, Groton, CT, 06340, USA.
  • Cook JC; Pfizer Drug Safety Research and Development, Eastern Point Road, Groton, CT, 06340, USA.
  • Radi Z; Pfizer Drug Safety Research and Development, 1 Portland Street, Cambridge, MA, 02139, USA.
  • Schuler M; Pfizer Drug Safety Research and Development, Eastern Point Road, Groton, CT, 06340, USA.
Regul Toxicol Pharmacol ; 123: 104934, 2021 Jul.
Article em En | MEDLINE | ID: mdl-33872740
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pele / Absorção Cutânea / Preparações Farmacêuticas Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pele / Absorção Cutânea / Preparações Farmacêuticas Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article