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Migalastat Tissue Distribution: Extrapolation From Mice to Humans Using Pharmacokinetic Modeling and Comparison With Agalsidase Beta Tissue Distribution in Mice.
Wu, Yi Shuan; Khanna, Richie; Schmith, Virginia; Lun, Yi; Shen, Jin-Song; Garcia, Anadina; Dungan, Leo; Perry, Anthony; Martin, Lukas; Tsai, Pai-Chi; Hamler, Rick; Das, Anibh M; Schiffmann, Raphael; Johnson, Franklin K.
Afiliação
  • Wu YS; Nuventra Pharma Sciences, Durham, North Carolina, USA.
  • Khanna R; Amicus Therapeutics, Inc., Cranbury, New Jersey, USA.
  • Schmith V; Nuventra Pharma Sciences, Durham, North Carolina, USA.
  • Lun Y; Amicus Therapeutics, Inc., Cranbury, New Jersey, USA.
  • Shen JS; Amicus Therapeutics, Inc., Cranbury, New Jersey, USA.
  • Garcia A; Amicus Therapeutics, Inc., Cranbury, New Jersey, USA.
  • Dungan L; Amicus Therapeutics, Inc., Cranbury, New Jersey, USA.
  • Perry A; Amicus Therapeutics, Inc., Cranbury, New Jersey, USA.
  • Martin L; Amicus Therapeutics, Inc., Cranbury, New Jersey, USA.
  • Tsai PC; Amicus Therapeutics, Inc., Cranbury, New Jersey, USA.
  • Hamler R; Amicus Therapeutics, Inc., Cranbury, New Jersey, USA.
  • Das AM; Clinic for Paediatric Nephrology, Hepatology and Metabolic Disorders, Hannover Medical School, Hannover, Germany.
  • Schiffmann R; Baylor Scott and White Research Institute, Dallas, Texas, USA.
  • Johnson FK; Amicus Therapeutics, Inc., Cranbury, New Jersey, USA.
Clin Pharmacol Drug Dev ; 10(9): 1075-1088, 2021 09.
Article em En | MEDLINE | ID: mdl-33876577
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: 1-Desoxinojirimicina / Alfa-Galactosidase / Isoenzimas / Modelos Biológicos Tipo de estudo: Prognostic_studies Limite: Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: 1-Desoxinojirimicina / Alfa-Galactosidase / Isoenzimas / Modelos Biológicos Tipo de estudo: Prognostic_studies Limite: Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article