Pharmacological inhibition of the primary endocannabinoid producing enzyme, DGL-&#945;, induces autism spectrum disorder-like and co-morbid phenotypes in adult C57BL/J mice.

Fyke, William; Alarcon, Juan Marcos; Velinov, Milen; Chadman, Kathryn K

Pharmacological inhibition of the primary endocannabinoid producing enzyme, DGL-α, induces autism spectrum disorder-like and co-morbid phenotypes in adult C57BL/J mice.

Fyke, William; Alarcon, Juan Marcos; Velinov, Milen; Chadman, Kathryn K.

Afiliação

Fyke W; Department of Developmental Neurobiology, New York State Institute for Basic Research in Developmental Disabilities, New York, New York, USA.
Alarcon JM; Graduate Program in Neural and Behavioral Science, SUNY Downstate Medical Center, Brooklyn, New York, USA.
Velinov M; George A. Jervis Clinic, NYS Institute for Basic Research in Developmental Disabilities (IBR), Staten Island, New York, USA.
Chadman KK; Graduate Program in Neural and Behavioral Science, SUNY Downstate Medical Center, Brooklyn, New York, USA.

Autism Res ; 14(7): 1375-1389, 2021 07.

Article em En | MEDLINE | ID: mdl-33886158

Assuntos

Transtorno do Espectro Autista; Endocanabinoides; Animais; Ansiedade; Modelos Animais de Doenças; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Fenótipo

Palavras-chave

DGL-α; autism spectrum disorders; endocannabinoids; mouse models; neurodevelopmental disorders

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Endocanabinoides / Transtorno do Espectro Autista Tipo de estudo: Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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