Downregulation of miR-218 by porcine reproductive and respiratory syndrome virus facilitates viral replication via inhibition of type I interferon responses.

Zhang, Lin; Zhang, Lu; Pan, Yu; Gao, Junxin; Xu, Yunfei; Li, Xi; Tian, Zhijun; Chen, Hongyan; Wang, Yue

Zhang, Lin; Zhang, Lu; Pan, Yu; Gao, Junxin; Xu, Yunfei; Li, Xi; Tian, Zhijun; Chen, Hongyan; Wang, Yue.

Afiliação

Zhang L; State Key Laboratory of Veterinary Biotechnology, National Poultry Laboratory Animal Resource Center, Heilongjiang Provincial Key Laboratory of Laboratory Animal and Comparative Medicine, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Zhang L; State Key Laboratory of Veterinary Biotechnology, National Poultry Laboratory Animal Resource Center, Heilongjiang Provincial Key Laboratory of Laboratory Animal and Comparative Medicine, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Pan Y; State Key Laboratory of Veterinary Biotechnology, National Poultry Laboratory Animal Resource Center, Heilongjiang Provincial Key Laboratory of Laboratory Animal and Comparative Medicine, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Gao J; State Key Laboratory of Veterinary Biotechnology, National Poultry Laboratory Animal Resource Center, Heilongjiang Provincial Key Laboratory of Laboratory Animal and Comparative Medicine, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Xu Y; State Key Laboratory of Veterinary Biotechnology, National Poultry Laboratory Animal Resource Center, Heilongjiang Provincial Key Laboratory of Laboratory Animal and Comparative Medicine, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Li X; State Key Laboratory of Veterinary Biotechnology, National Poultry Laboratory Animal Resource Center, Heilongjiang Provincial Key Laboratory of Laboratory Animal and Comparative Medicine, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Tian Z; State Key Laboratory of Veterinary Biotechnology, National Poultry Laboratory Animal Resource Center, Heilongjiang Provincial Key Laboratory of Laboratory Animal and Comparative Medicine, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Chen H; State Key Laboratory of Veterinary Biotechnology, National Poultry Laboratory Animal Resource Center, Heilongjiang Provincial Key Laboratory of Laboratory Animal and Comparative Medicine, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Wang Y; State Key Laboratory of Veterinary Biotechnology, National Poultry Laboratory Animal Resource Center, Heilongjiang Provincial Key Laboratory of Laboratory Animal and Comparative Medicine, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China. Electronic addres

J Biol Chem ; 296: 100683, 2021.

Article em En | MEDLINE | ID: mdl-33887325

Assuntos

Regulação para Baixo; Interferon Tipo I/metabolismo; Macrófagos Alveolares/virologia; MicroRNAs/genética; Vírus da Síndrome Respiratória e Reprodutiva Suína/fisiologia; Replicação Viral; Animais; Linhagem Celular; Macrófagos Alveolares/metabolismo; Proteína 3 Supressora da Sinalização de Citocinas/metabolismo

Palavras-chave

hostvirus interaction; miR-218; porcine reproductive and respiratory syndrome virus; suppressor of cytokine signaling 3 (SOCS3); type I interferon response

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Replicação Viral / Interferon Tipo I / Regulação para Baixo / Macrófagos Alveolares / Vírus da Síndrome Respiratória e Reprodutiva Suína / MicroRNAs Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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