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Steroidal alkaloids isolated from Veratrum grandiflorum Loes. as novel Smoothened inhibitors with anti-proliferation effects on DAOY medulloblastoma cells.
Gao, Li Juan; Zhang, Meng Zhen; Li, Xiao Yu; Huang, Wen Kang; Xu, Shi Fang; Ye, Yi Ping.
Afiliação
  • Gao LJ; Key Laboratory of Neuropsychiatric Drug Research of Zhejiang Province, Institute of Materia Medica, Hangzhou Medical College, Hangzhou, Zhejiang 310013, China.
  • Zhang MZ; Key Laboratory of Neuropsychiatric Drug Research of Zhejiang Province, Institute of Materia Medica, Hangzhou Medical College, Hangzhou, Zhejiang 310013, China.
  • Li XY; Key Laboratory of Neuropsychiatric Drug Research of Zhejiang Province, Institute of Materia Medica, Hangzhou Medical College, Hangzhou, Zhejiang 310013, China.
  • Huang WK; Key Laboratory of Neuropsychiatric Drug Research of Zhejiang Province, Institute of Materia Medica, Hangzhou Medical College, Hangzhou, Zhejiang 310013, China.
  • Xu SF; Key Laboratory of Neuropsychiatric Drug Research of Zhejiang Province, Institute of Materia Medica, Hangzhou Medical College, Hangzhou, Zhejiang 310013, China.
  • Ye YP; Key Laboratory of Neuropsychiatric Drug Research of Zhejiang Province, Institute of Materia Medica, Hangzhou Medical College, Hangzhou, Zhejiang 310013, China. Electronic address: yeyiping2005@163.com.
Bioorg Med Chem ; 39: 116166, 2021 06 01.
Article em En | MEDLINE | ID: mdl-33910157
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esteroides / Veratrum / Proliferação de Células / Alcaloides / Receptor Smoothened / Meduloblastoma Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esteroides / Veratrum / Proliferação de Células / Alcaloides / Receptor Smoothened / Meduloblastoma Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article