Plasticity of Naturally Occurring Regulatory T Cells in Allergic Airway Disease Is Modulated by the Transcriptional Activity of <i>Il-6</i>.

MacBeth, Morgan; Joetham, Anthony; Gelfand, Erwin W; Schedel, Michaela

Plasticity of Naturally Occurring Regulatory T Cells in Allergic Airway Disease Is Modulated by the Transcriptional Activity of Il-6.

MacBeth, Morgan; Joetham, Anthony; Gelfand, Erwin W; Schedel, Michaela.

Afiliação

MacBeth M; Division of Allergy and Immunology and Cell Biology, Department of Pediatrics, National Jewish Health, Denver, CO 80206, USA.
Joetham A; Department of Medical Oncology, University of Colorado, Denver, CO 80206, USA.
Gelfand EW; Division of Allergy and Immunology and Cell Biology, Department of Pediatrics, National Jewish Health, Denver, CO 80206, USA.
Schedel M; Division of Allergy and Immunology and Cell Biology, Department of Pediatrics, National Jewish Health, Denver, CO 80206, USA.

Int J Mol Sci ; 22(9)2021 Apr 27.

Article em En | MEDLINE | ID: mdl-33925531

Assuntos

Hipersensibilidade/imunologia; Interleucina-6/imunologia; Pneumopatias/imunologia; Linfócitos T Reguladores/metabolismo; Adaptação Fisiológica/imunologia; Animais; Plasticidade Celular/genética; Plasticidade Celular/imunologia; Citocinas/imunologia; Interleucina-10/imunologia; Interleucina-6/genética; Pneumopatias/genética; Pneumopatias/metabolismo; Masculino; Camundongos; Camundongos Endogâmicos C57BL; NF-kappa B/imunologia; Regiões Promotoras Genéticas; Linfócitos T Reguladores/imunologia; Fator de Necrose Tumoral alfa/metabolismo

Palavras-chave

IL-6; naturally occurring T regulatory cells (nTregs); plasticity; transcription factor binding; transcriptional regulation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interleucina-6 / Linfócitos T Reguladores / Hipersensibilidade / Pneumopatias Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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