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The ZEB2-dependent EMT transcriptional programme drives therapy resistance by activating nucleotide excision repair genes ERCC1 and ERCC4 in colorectal cancer.
Sreekumar, Rahul; Al-Saihati, Hajir; Emaduddin, Muhammad; Moutasim, Karwan; Mellone, Massimiliano; Patel, Ashish; Kilic, Seval; Cetin, Metin; Erdemir, Sule; Navio, Marta Salgado; Lopez, Maria Antonette; Curtis, Nathan; Yagci, Tamer; Primrose, John N; Price, Brendan D; Berx, Geert; Thomas, Gareth J; Tulchinsky, Eugene; Mirnezami, Alex; Sayan, A Emre.
Afiliação
  • Sreekumar R; Cancer Sciences Division, University of Southampton, UK.
  • Al-Saihati H; Cancer Sciences Division, University of Southampton, UK.
  • Emaduddin M; College of Applied Medical Sciences, University of Hafr Al-Batin, Saudi Arabia.
  • Moutasim K; Cancer Sciences Division, University of Southampton, UK.
  • Mellone M; Cancer Sciences Division, University of Southampton, UK.
  • Patel A; Cancer Sciences Division, University of Southampton, UK.
  • Kilic S; Cancer Sciences Division, University of Southampton, UK.
  • Cetin M; Cancer Sciences Division, University of Southampton, UK.
  • Erdemir S; Department of Molecular Biology and Genetics, Gebze Technical University, Turkey.
  • Navio MS; Department of Molecular Biology and Genetics, Gebze Technical University, Turkey.
  • Lopez MA; Cancer Sciences Division, University of Southampton, UK.
  • Curtis N; Cancer Sciences Division, University of Southampton, UK.
  • Yagci T; Department of Surgery, Southampton University Hospital NHS Trust, UK.
  • Primrose JN; Department of Molecular Biology and Genetics, Gebze Technical University, Turkey.
  • Price BD; Cancer Sciences Division, University of Southampton, UK.
  • Berx G; Department of Surgery, Southampton University Hospital NHS Trust, UK.
  • Thomas GJ; Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Tulchinsky E; Molecular Cellular Oncology Lab, Department for Biomedical Molecular Biology, Ghent University, Belgium.
  • Mirnezami A; Cancer Research Institute Ghent (CRIG), Belgium.
  • Sayan AE; Cancer Sciences Division, University of Southampton, UK.
Mol Oncol ; 15(8): 2065-2083, 2021 08.
Article em En | MEDLINE | ID: mdl-33931939
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transcrição Gênica / Neoplasias Colorretais / Protocolos de Quimioterapia Combinada Antineoplásica / Proteínas de Ligação a DNA / Reparo do DNA / Endonucleases / Transição Epitelial-Mesenquimal / Homeobox 2 de Ligação a E-box com Dedos de Zinco Tipo de estudo: Clinical_trials / Guideline / Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transcrição Gênica / Neoplasias Colorretais / Protocolos de Quimioterapia Combinada Antineoplásica / Proteínas de Ligação a DNA / Reparo do DNA / Endonucleases / Transição Epitelial-Mesenquimal / Homeobox 2 de Ligação a E-box com Dedos de Zinco Tipo de estudo: Clinical_trials / Guideline / Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article