Expression of therapy-induced senescence markers in breast cancer samples upon incomplete response to neoadjuvant chemotherapy.

Saleh, Tareq; Alhesa, Ahmad; Al-Balas, Mahmoud; Abuelaish, Omar; Mansour, Ahmad; Awad, Heyam; El-Sadoni, Mohammed; Carpenter, Valerie J; Azab, Bilal

Saleh, Tareq; Alhesa, Ahmad; Al-Balas, Mahmoud; Abuelaish, Omar; Mansour, Ahmad; Awad, Heyam; El-Sadoni, Mohammed; Carpenter, Valerie J; Azab, Bilal.

Afiliação

Saleh T; Department of Basic Medical Sciences, Faculty of Medicine, The Hashemite University, Zarqa 13133, Jordan.
Alhesa A; Department of Pathology, Microbiology, and Forensic Medicine, School of Medicine, The University of Jordan, Amman 11942, Jordan.
Al-Balas M; Department of General and Special Surgery, Faculty of Medicine, The Hashemite University, Zarqa 13133, Jordan.
Abuelaish O; Department of General Surgery, Royal Medical Services, Amman, Jordan.
Mansour A; Department of Pathology, Microbiology, and Forensic Medicine, School of Medicine, The University of Jordan, Amman 11942, Jordan.
Awad H; Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH 45219, U.S.A.
El-Sadoni M; Department of Pathology, Microbiology, and Forensic Medicine, School of Medicine, The University of Jordan, Amman 11942, Jordan.
Carpenter VJ; Department of Pathology, Microbiology, and Forensic Medicine, School of Medicine, The University of Jordan, Amman 11942, Jordan.
Azab B; Department of Pharmacology and Toxicology, School of Medicine, Virginia Commonwealth University, Richmond, VA 23298, U.S.A.

Biosci Rep ; 41(5)2021 05 28.

Article em En | MEDLINE | ID: mdl-33948615

Assuntos

Biomarcadores Tumorais/metabolismo; Neoplasias da Mama/genética; Senescência Celular; Terapia Neoadjuvante; Biomarcadores Tumorais/genética; Neoplasias da Mama/tratamento farmacológico; Neoplasias da Mama/metabolismo; Neoplasias da Mama/patologia; Inibidor de Quinase Dependente de Ciclina p21/genética; Inibidor de Quinase Dependente de Ciclina p21/metabolismo; Feminino; Código das Histonas; Humanos; Lamina Tipo B/genética; Lamina Tipo B/metabolismo; Metilação; Pessoa de Meia-Idade

Palavras-chave

H3K9Me3; Lamin B1; Neoadjuvant Chemotherapy; Senescence; breast cancers; p21CIP1

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Biomarcadores Tumorais / Senescência Celular / Terapia Neoadjuvante Tipo de estudo: Prognostic_studies Limite: Female / Humans / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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