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Nanoparticle-mediated tumor cell expression of mIL-12 via systemic gene delivery treats syngeneic models of murine lung cancers.
Ahn, Hye-Hyun; Carrington, Christine; Hu, Yizong; Liu, Heng-Wen; Ng, Christy; Nam, Hwanhee; Park, Andrew; Stace, Catherine; West, Will; Mao, Hai-Quan; Pomper, Martin G; Ullman, Christopher G; Minn, Il.
Afiliação
  • Ahn HH; Division of Nuclear Medicine and Molecular Imaging, Russel H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, School of Medicine, Baltimore, MD, 21205, USA.
  • Carrington C; Cancer Targeting Systems, 1188 Centre Street, Newton Centre, MA, 02459, USA.
  • Hu Y; Department of Biomedical Engineering, Translational Tissue Engineering Center, Johns Hopkins University, School of Medicine, Baltimore, MD, 21287, USA.
  • Liu HW; Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD, 21218, USA.
  • Ng C; Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD, 21218, USA.
  • Nam H; Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD, 21218, USA.
  • Park A; Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD, 21218, USA.
  • Stace C; Division of Nuclear Medicine and Molecular Imaging, Russel H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, School of Medicine, Baltimore, MD, 21205, USA.
  • West W; Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD, 21218, USA.
  • Mao HQ; Division of Nuclear Medicine and Molecular Imaging, Russel H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, School of Medicine, Baltimore, MD, 21205, USA.
  • Pomper MG; AstraZeneca (MedImmune), One Medimmune Way, Gaithersburg, MD, 20878, USA.
  • Ullman CG; Cancer Targeting Systems, 1188 Centre Street, Newton Centre, MA, 02459, USA.
  • Minn I; Platform First Ltd, 1 Station Road, Sutton, Cambridge, CB6 2RL, UK.
Sci Rep ; 11(1): 9733, 2021 05 06.
Article em En | MEDLINE | ID: mdl-33958660
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA / Terapia Genética / Técnicas de Transferência de Genes / Interleucina-12 / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA / Terapia Genética / Técnicas de Transferência de Genes / Interleucina-12 / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article