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1,2,4-Triazolo[1,5-a]pyrimidines: Efficient one-step synthesis and functionalization as influenza polymerase PA-PB1 interaction disruptors.
Pismataro, Maria Chiara; Felicetti, Tommaso; Bertagnin, Chiara; Nizi, Maria Giulia; Bonomini, Anna; Barreca, Maria Letizia; Cecchetti, Violetta; Jochmans, Dirk; De Jonghe, Steven; Neyts, Johan; Loregian, Arianna; Tabarrini, Oriana; Massari, Serena.
Afiliação
  • Pismataro MC; Department of Pharmaceutical Sciences, University of Perugia, Via Del Liceo 1, 06123, Perugia, Italy.
  • Felicetti T; Department of Pharmaceutical Sciences, University of Perugia, Via Del Liceo 1, 06123, Perugia, Italy.
  • Bertagnin C; Department of Molecular Medicine, University of Padua, Via Gabelli 63, 35121, Padua, Italy.
  • Nizi MG; Department of Pharmaceutical Sciences, University of Perugia, Via Del Liceo 1, 06123, Perugia, Italy.
  • Bonomini A; Department of Molecular Medicine, University of Padua, Via Gabelli 63, 35121, Padua, Italy.
  • Barreca ML; Department of Pharmaceutical Sciences, University of Perugia, Via Del Liceo 1, 06123, Perugia, Italy.
  • Cecchetti V; Department of Pharmaceutical Sciences, University of Perugia, Via Del Liceo 1, 06123, Perugia, Italy.
  • Jochmans D; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Herestraat 49, Box 1043, 3000, Leuven, Belgium.
  • De Jonghe S; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Herestraat 49, Box 1043, 3000, Leuven, Belgium.
  • Neyts J; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Herestraat 49, Box 1043, 3000, Leuven, Belgium.
  • Loregian A; Department of Molecular Medicine, University of Padua, Via Gabelli 63, 35121, Padua, Italy.
  • Tabarrini O; Department of Pharmaceutical Sciences, University of Perugia, Via Del Liceo 1, 06123, Perugia, Italy.
  • Massari S; Department of Pharmaceutical Sciences, University of Perugia, Via Del Liceo 1, 06123, Perugia, Italy. Electronic address: serena.massari@unipg.it.
Eur J Med Chem ; 221: 113494, 2021 Oct 05.
Article em En | MEDLINE | ID: mdl-33962311
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Pirimidinas / Triazóis / Proteínas Virais / RNA Polimerase Dependente de RNA / Multimerização Proteica Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Pirimidinas / Triazóis / Proteínas Virais / RNA Polimerase Dependente de RNA / Multimerização Proteica Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article