The Impact of Insulin Resistance on Cardiovascular Control During Exercise in Diabetes.

Mizuno, Masaki; Hotta, Norio; Ishizawa, Rie; Kim, Han-Kyul; Iwamoto, Gary; Vongpatanasin, Wanpen; Mitchell, Jere H; Smith, Scott A

Mizuno, Masaki; Hotta, Norio; Ishizawa, Rie; Kim, Han-Kyul; Iwamoto, Gary; Vongpatanasin, Wanpen; Mitchell, Jere H; Smith, Scott A.

Afiliação

Ishizawa R; Department of Applied Clinical Research.
Kim HK; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX.
Iwamoto G; Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX.
Vongpatanasin W; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX.
Mitchell JH; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX.

Exerc Sport Sci Rev ; 49(3): 157-167, 2021 07 01.

Article em En | MEDLINE | ID: mdl-33965976

ABSTRACT

ABSTRACT

Patients with diabetes display heightened blood pressure response to exercise, but the underlying mechanism remains to be elucidated. There is no direct evidence that insulin resistance (hyperinsulinemia or hyperglycemia) impacts neural cardiovascular control during exercise. We propose a novel paradigm in which hyperinsulinemia or hyperglycemia significantly influences neural regulatory pathways controlling the circulation during exercise in diabetes.

Assuntos

Diabetes Mellitus Tipo 2; Diabetes Mellitus; Hiperglicemia; Hiperinsulinismo; Resistência à Insulina; Exercício Físico; Humanos; Insulina

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Resistência à Insulina / Diabetes Mellitus / Diabetes Mellitus Tipo 2 / Hiperglicemia / Hiperinsulinismo Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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