Structural analysis and biological effects of a neutral polysaccharide from the fruits of Rosa laevigata.

Zhang, Jiaojiao; Song, Ziteng; Li, Ying; Zhang, Shaojie; Bao, Jiahe; Wang, Honglin; Dong, Caixia; Ohizumi, Yasushi; Xu, Jing; Guo, Yuanqiang

Zhang, Jiaojiao; Song, Ziteng; Li, Ying; Zhang, Shaojie; Bao, Jiahe; Wang, Honglin; Dong, Caixia; Ohizumi, Yasushi; Xu, Jing; Guo, Yuanqiang.

Afiliação

Zhang J; State Key Laboratory of Medicinal Chemistry Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin, 300350, People's Republic of China.
Song Z; State Key Laboratory of Medicinal Chemistry Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin, 300350, People's Republic of China.
Li Y; State Key Laboratory of Medicinal Chemistry Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin, 300350, People's Republic of China.
Zhang S; State Key Laboratory of Medicinal Chemistry Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin, 300350, People's Republic of China.
Bao J; State Key Laboratory of Medicinal Chemistry Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin, 300350, People's Republic of China.
Wang H; State Key Laboratory of Medicinal Chemistry Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin, 300350, People's Republic of China.
Dong C; Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnosis, School of Pharmacy, Tianjin Medical University, Tianjin, 300070, People's Republic of China.
Ohizumi Y; Kansei Fukushi Research Institute, Tohoku Fukushi University, Sendai, 989-3201, Japan.
Xu J; State Key Laboratory of Medicinal Chemistry Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin, 300350, People's Republic of China. Electronic address: Xujing611@nankai.edu.cn.
Guo Y; State Key Laboratory of Medicinal Chemistry Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin, 300350, People's Republic of China. Electronic address: victgyq@nankai.edu.cn.

Carbohydr Polym ; 265: 118080, 2021 Aug 01.

Article em En | MEDLINE | ID: mdl-33966844

Assuntos

Frutas/química; Polissacarídeos/química; Polissacarídeos/farmacologia; Rosa/química; Animais; Antineoplásicos/farmacologia; Movimento Celular/efeitos dos fármacos; Proliferação de Células/efeitos dos fármacos; Humanos; Fatores Imunológicos/farmacologia; Imunomodulação/efeitos dos fármacos; Células K562; Camundongos; Peso Molecular; Monossacarídeos/análise; Óxido Nítrico/análise; Células RAW 264.7; Espécies Reativas de Oxigênio; Peixe-Zebra

Palavras-chave

2', 7'-Dichlorofluorescein diacetate (PubChem CID: 104913); 3-Amino, 4-aminomethyl-2', 7'-difluorescein diacetate (PubChem CID: 2762646); Antitumor activity; Chloroform (PubChem CID: 6212); Dimethyl sulfoxide (PubChem CID: 679); Immunoregulatory activity; Methyl iodide (PubChem CID: 6328); Neutral polysaccharide; Rosa laevigata; Sodium borohydride (PubChem CID: 4311764); Sodium chloride (PubChem CID: 5234); Thiazolyl blue tetrazolium bromide (PubChem CID: 64965); Tricaine (PubChem CID: 261501); Trifluoroacetic acid (PubChem CID: 6422); Zebrafish xenograft model

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polissacarídeos / Rosa / Frutas Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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