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Loss of diacylglycerol kinase ε causes thrombotic microangiopathy by impairing endothelial VEGFA signaling.
Liu, Dingxiao; Ding, Qiong; Dai, Dao-Fu; Padhy, Biswajit; Nayak, Manasa K; Li, Can; Purvis, Madison; Jin, Heng; Shu, Chang; Chauhan, Anil K; Huang, Chou-Long; Attanasio, Massimo.
Afiliação
  • Liu D; Department of Internal Medicine, University of Iowa, Iowa City, Iowa, USA.
  • Ding Q; Department of Vascular Surgery, The Second Xiangya Hospital, Central South University, Changsha, China.
  • Dai DF; Department of Internal Medicine, University of Iowa, Iowa City, Iowa, USA.
  • Padhy B; Department of Pathology, University of Iowa, Iowa City, Iowa, USA.
  • Nayak MK; Department of Internal Medicine, University of Iowa, Iowa City, Iowa, USA.
  • Li C; Department of Internal Medicine, University of Iowa, Iowa City, Iowa, USA.
  • Purvis M; Department of Internal Medicine, University of Iowa, Iowa City, Iowa, USA.
  • Jin H; Department of Internal Medicine, University of Iowa, Iowa City, Iowa, USA.
  • Shu C; Department of Emergency Medicine, Tianjin Medical University General Hospital, Tianjin, China.
  • Chauhan AK; Department of Vascular Surgery, The Second Xiangya Hospital, Central South University, Changsha, China.
  • Huang CL; Department of Internal Medicine, University of Iowa, Iowa City, Iowa, USA.
  • Attanasio M; Department of Internal Medicine, University of Iowa, Iowa City, Iowa, USA.
JCI Insight ; 6(9)2021 05 10.
Article em En | MEDLINE | ID: mdl-33986189
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Endotélio Vascular / Diacilglicerol Quinase / Receptor 2 de Fatores de Crescimento do Endotélio Vascular / Fator A de Crescimento do Endotélio Vascular / Proteínas Proto-Oncogênicas c-akt / Síndrome Hemolítico-Urêmica Atípica Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Endotélio Vascular / Diacilglicerol Quinase / Receptor 2 de Fatores de Crescimento do Endotélio Vascular / Fator A de Crescimento do Endotélio Vascular / Proteínas Proto-Oncogênicas c-akt / Síndrome Hemolítico-Urêmica Atípica Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article