Nanopore sensing: A physical-chemical approach.
Biochim Biophys Acta Biomembr
; 1863(9): 183644, 2021 09 01.
Article
em En
| MEDLINE
| ID: mdl-33989531
ABSTRACT
Protein nanopores have emerged as an important class of sensors for the understanding of biophysical processes, such as molecular transport across membranes, and for the detection and characterization of biopolymers. Here, we trace the development of these sensors from the Coulter counter and squid axon studies to the modern applications including exquisite detection of small volume changes and molecular reactions at the single molecule (or reactant) scale. This review focuses on the chemistry of biological pores, and how that influences the physical chemistry of molecular detection.
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1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Nanoporos
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article