Ancestry matters: Building inclusivity into preclinical study design.
Cell
; 184(10): 2525-2531, 2021 05 13.
Article
em En
| MEDLINE
| ID: mdl-33989545
ABSTRACT
Human cell lines (CLs) are key assets for biomedicine but lack ancestral diversity. Here, we explore why genetic diversity among cell-based models is essential for making preclinical research more equitable and widely translatable. We lay out practical actions that can be taken to improve inclusivity in study design.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Negro ou Afro-Americano
/
Linhagem Celular
/
Pesquisa Biomédica
/
População Branca
/
Medicina de Precisão
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article