[Postoperative Recurrence of ROS1âPositive Pulmonary Adenocarcinoma after 19 Years].
Gan To Kagaku Ryoho
; 48(5): 685-687, 2021 May.
Article
em Ja
| MEDLINE
| ID: mdl-34006714
ABSTRACT
A 73âyearâold woman underwent right lower lobectomy for Stage â
A(pathological Stage T1N0M0)pulmonary adenocarcinoma. After 19 years, she complained of dyspnea on exertion. Computed tomography revealed metastatic lesions in the bilateral supraclavicular, mediastinal, and hilar lymph nodes. Thoracoscopic lymph node biopsy showed recurrence of the adenocarcinoma, and immunohistochemical staining confirmed that the metastases were ROS1âpositive. The patient responded well to crizotinib therapy. The prognosis of nonâsmallâcell lung cancer is considered favorable when it does not recur within 5 years, postoperation. However, few studies have reported the recurrence of ROS1âpositive pulmonary adenocarcinoma after a long diseaseâfree interval. Longâterm postoperative followâup is essential for patients with ROS1âpositive pulmonary adenocarcinomas.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Adenocarcinoma
/
Carcinoma Pulmonar de Células não Pequenas
/
Neoplasias Pulmonares
Tipo de estudo:
Prognostic_studies
Limite:
Aged
/
Female
/
Humans
Idioma:
Ja
Ano de publicação:
2021
Tipo de documento:
Article