MicroRNA-124-3p attenuates the development of nerve injury-induced neuropathic pain by targeting early growth response 1 in the dorsal root ganglia and spinal dorsal horn.

Jiang, Mingjun; Zhang, Xuan; Wang, Xueli; Xu, Feng; Zhang, Jian; Li, Liren; Xie, Xiaohang; Wang, Li; Yang, Yin; Xu, Ji-Tian

Jiang, Mingjun; Zhang, Xuan; Wang, Xueli; Xu, Feng; Zhang, Jian; Li, Liren; Xie, Xiaohang; Wang, Li; Yang, Yin; Xu, Ji-Tian.

Afiliação

Jiang M; Department of Physiology and Neurobiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.
Zhang X; Department of Physiology and Neurobiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.
Wang X; Department of Physiology and Neurobiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.
Xu F; Department of Physiology and Neurobiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.
Zhang J; Department of Renal Transplantation, The Seventh People's Hospital of Zhengzhou, Zhengzhou, China.
Li L; Department of Physiology and Neurobiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.
Xie X; Department of Physiology and Neurobiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.
Wang L; Department of Physiology and Neurobiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.
Xu JT; Department of Physiology and Neurobiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.

J Neurochem ; 158(4): 928-942, 2021 08.

Article em En | MEDLINE | ID: mdl-34008206

Assuntos

Proteína 1 de Resposta de Crescimento Precoce/efeitos dos fármacos; Gânglios Espinais/efeitos dos fármacos; Terapia Genética/métodos; MicroRNAs/uso terapêutico; Neuralgia/terapia; Células do Corno Posterior/efeitos dos fármacos; Regiões 3' não Traduzidas/genética; Animais; Comportamento Animal/efeitos dos fármacos; Técnicas de Transferência de Genes; Hiperalgesia/prevenção & controle; Ligadura; Masculino; Neuralgia/psicologia; Traumatismos dos Nervos Periféricos; Ratos; Ratos Sprague-Dawley; Nervos Espinhais/lesões

Palavras-chave

dorsal root ganglia; early growth response 1; miR-124-3p; neuropathic pain; spinal cord; spinal nerve ligation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Terapia Genética / Células do Corno Posterior / MicroRNAs / Proteína 1 de Resposta de Crescimento Precoce / Gânglios Espinais / Neuralgia Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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