Cargo receptor-assisted endoplasmic reticulum export of pathogenic &#945;1-antitrypsin polymers.

Ordóñez, Adriana; Harding, Heather P; Marciniak, Stefan J; Ron, David

Cargo receptor-assisted endoplasmic reticulum export of pathogenic α1-antitrypsin polymers.

Ordóñez, Adriana; Harding, Heather P; Marciniak, Stefan J; Ron, David.

Afiliação

Ordóñez A; Cambridge Institute for Medical Research (CIMR), University of Cambridge, Cambridge Biomedical Campus, The Keith Peters Building, Cambridge CB2 0XY, UK. Electronic address: aog23@cam.ac.uk.
Harding HP; Cambridge Institute for Medical Research (CIMR), University of Cambridge, Cambridge Biomedical Campus, The Keith Peters Building, Cambridge CB2 0XY, UK.
Marciniak SJ; Cambridge Institute for Medical Research (CIMR), University of Cambridge, Cambridge Biomedical Campus, The Keith Peters Building, Cambridge CB2 0XY, UK.
Ron D; Cambridge Institute for Medical Research (CIMR), University of Cambridge, Cambridge Biomedical Campus, The Keith Peters Building, Cambridge CB2 0XY, UK.

Cell Rep ; 35(7): 109144, 2021 05 18.

Article em En | MEDLINE | ID: mdl-34010647

Assuntos

Retículo Endoplasmático/metabolismo; Polímeros/metabolismo; alfa 1-Antitripsina/metabolismo; Humanos

Palavras-chave

CHO CRISPR-Cas9 library; CHO cells; ERGIC-53; LMAN1; SURF4; cargo receptors; endoplasmic reticulum; genome-wide CRISPR-Cas9 screen; polymer trafficking; α1-antitrypsin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polímeros / Alfa 1-Antitripsina / Retículo Endoplasmático Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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