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Safety and efficacy of upadacitinib in combination with topical corticosteroids in adolescents and adults with moderate-to-severe atopic dermatitis (AD Up): results from a randomised, double-blind, placebo-controlled, phase 3 trial.
Reich, Kristian; Teixeira, Henrique D; de Bruin-Weller, Marjolein; Bieber, Thomas; Soong, Weily; Kabashima, Kenji; Werfel, Thomas; Zeng, Jiewei; Huang, Xiaohong; Hu, Xiaofei; Hendrickson, Barbara A; Ladizinski, Barry; Chu, Alvina D; Silverberg, Jonathan I.
Afiliação
  • Reich K; Translational Research in Inflammatory Skin Diseases, Institute for Health Services Research in Dermatology and Nursing, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Electronic address: k.reich@uke.de.
  • Teixeira HD; AbbVie, North Chicago, IL, USA.
  • de Bruin-Weller M; Department of Dermatology and Allergology, National Expertise Center of Atopic Dermatitis, University Medical Center Utrecht, Utrecht, Netherlands.
  • Bieber T; Department of Dermatology and Allergy, University Hospital of Bonn, Bonn, Germany.
  • Soong W; Alabama Allergy and Asthma Center and Clinical Research Center of Alabama, Birmingham, AL, USA.
  • Kabashima K; Department of Dermatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Werfel T; Department of Dermatology and Allergy, Division of Immunodermatology and Allergy Research, Hannover Medical School, Hannover, Germany.
  • Zeng J; AbbVie, North Chicago, IL, USA.
  • Huang X; AbbVie, North Chicago, IL, USA.
  • Hu X; AbbVie, North Chicago, IL, USA.
  • Hendrickson BA; AbbVie, North Chicago, IL, USA.
  • Ladizinski B; AbbVie, North Chicago, IL, USA.
  • Chu AD; AbbVie, North Chicago, IL, USA.
  • Silverberg JI; Department of Dermatology, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Lancet ; 397(10290): 2169-2181, 2021 06 05.
Article em En | MEDLINE | ID: mdl-34023009
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Índice de Gravidade de Doença / Corticosteroides / Dermatite Atópica / Quimioterapia Combinada / Inibidores de Janus Quinases / Compostos Heterocíclicos com 3 Anéis Tipo de estudo: Clinical_trials Limite: Adult / Female / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Índice de Gravidade de Doença / Corticosteroides / Dermatite Atópica / Quimioterapia Combinada / Inibidores de Janus Quinases / Compostos Heterocíclicos com 3 Anéis Tipo de estudo: Clinical_trials Limite: Adult / Female / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article